MURINE CD38 - AN IMMUNOREGULATORY ECTOENZYME

被引：85

作者：

LUND, F ^{[1
]}

SOLVASON, N ^{[1
]}

GRIMALDI, JC ^{[1
]}

PARKHOUSE, RME ^{[1
]}

HOWARD, M ^{[1
]}

机构：

[1] INST ANIM HLTH,DIV IMMUNOL,WOKING GU24 0NF,SURREY,ENGLAND

来源：

IMMUNOLOGY TODAY | 1995年 / 16卷 / 10期

关键词：

D O I：

10.1016/0167-5699(95)80029-8

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

CD38 is an ectoenxyme that utilizes NAD(+) and is expressed by many cells of hematopoietic origin. Antibodies to CD38 Potentiate many biological activities on lymphocytes, including induction of murine B-cell proliferation. In this article, Frances Lund and colleagues summarize information concerning the expression, enzymatic activity and signal transduction pathway utilized by murine CD38.

引用

页码：469 / 473

页数：5

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