NEW METHOD OF QUATERNIZING AMINES AND ITS USE IN AMINO-ACID AND PEPTIDE CHEMISTRY

被引：105

作者：

CHEN, FCM ^{[1
]}

BENOITON, NL ^{[1
]}

机构：

[1] UNIV OTTAWA,DEPT BIOCHEM,OTTAWA K1N 9A9,ONTARIO,CANADA

来源：

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE | 1976年 / 54卷 / 20期

关键词：

Peptides - Potassium compounds;

D O I：

10.1139/v76-475

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Methyl iodide and potassium bicarbonate in methanol is presented as a mild, efficient, and selective reagent for the quaternization of amino groups. It does not attack hydroxyl groups. Its use with amino acids, derivatives of lysine, and small peptides is described.

引用

页码：3310 / 3311

页数：2

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