NONLINEAR DYNAMICS OF ELECTROCARDIOGRAPHIC WAVE-FORMS FOLLOWING COCAINE ADMINISTRATION

被引：5

作者：

GARFINKEL, AJ

WALTER, DO

TRELEASE, RB

HARPER, RK

HARPER, RM

机构：

[1] UNIV CALIF LOS ANGELES,SCH MED,DEPT ANAT & CELL BIOL,LOS ANGELES,CA 90024

[2] UNIV CALIF LOS ANGELES,SCH MED,BRAIN RES INST,LOS ANGELES,CA 90024

来源：

LIFE SCIENCES | 1991年 / 48卷 / 22期

关键词：

D O I：

10.1016/0024-3205(91)90153-3

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We examined dynamics of ECG waveforms preceding and following 10 mg/kg intravenous administration of cocaine in freely moving cats. Cocaine induced substantial variation in ECG waveforms, as demonstrated by non-linear procedures of phase-plane plots and Poincare analyses. Phase-plane plots revealed that waveform variation following cocaine administration was not randomly or uniformly distributed, but instead followed patterns of clustered organization with unvisited regions. These patterns are characteristic of chaotic distributions, and support the hypothesis that ECG waveform variation following cocaine does not degenerate into random patterns; instead, the variation follows deterministic, though chaotic patterns.

引用

页码：2189 / 2193

页数：5