EVALUATION OF THE EFFECT OF PANCREATIC RESECTION IN ADVANCED PANCREATIC-CANCER WITH SPECIAL REFERENCE USING HOSPITAL-FREE SURVIVAL AS A MEASURE OF QUALITY-OF-LIFE

被引：0

作者：

YASUE, M ^{[1
]}

SAKAMOTO, J ^{[1
]}

MORIMOTO, T ^{[1
]}

YASUI, K ^{[1
]}

KUNO, N ^{[1
]}

KURIMOTO, K ^{[1
]}

TERAMUKAI, S ^{[1
]}

OHASHI, Y ^{[1
]}

机构：

[1] AICHI PREFECTURAL HOSP,DEPT SURG,OKAZAKI,AICHI 444,JAPAN

来源：

JAPANESE JOURNAL OF CLINICAL ONCOLOGY | 1995年 / 25卷 / 02期

关键词：

PANCREATIC CANCER; SURVIVAL; HOSPITAL-FREE SURVIVAL; PANCREATIC RESECTION; PROGNOSTIC FACTORS;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Comparisons of surgical procedures and the identification of prognostic factors in pancreatic cancer were carried out on 158 patients who underwent surgery in Aichi Cancer Center from 1975 to 1991 for advanced pancreatic ductal adenocarcinoma. Survival and 'hospital-free survival (HFS),(1) which we consider the best general means of measuring quality of life (QOL) in such severe and often fatal disease, were identified as primary end points, and the effect of pancreatectomy, compared with palliative surgery (by-pass operation, etc.) for TNM Stages III and IV pancreatic Cancer was evaluated. Both survival and HFS were significantly longer in the group of patients who underwent panreatectomies (R group, n 25) compared to the group without pancreatic resections (NR group, n 35) in Stage III cases. In Stage IV cases, however, no significant difference was observed between the R (n 12) and NR (n 86) groups. From these results, we conclude that an extensive pancreatic resection against Stage III pancreatic cancer may improve prognosis. For Stage IV pancreatic cancers, however, agressive surgery might not always be beneficial either for survival or for QOL.

引用

页码：37 / 45

页数：9