INTRAMOLECULAR BAYLIS-HILLMAN REACTION - A PATHWAY TO SUBSTITUTED COUMARINS

被引：77

作者：

DREWES, SE

NJAMELA, OL

EMSLIE, ND

RAMESAR, N

FIELD, JS

机构：

[1] Department of Chemistry, University of Natal, Pietermaritzburg, 3200

来源：

SYNTHETIC COMMUNICATIONS | 1993年 / 23卷 / 20期

关键词：

D O I：

10.1080/00397919308012600

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The acrylate ester of salicylaldehyde, in the presence of DABCO, affords a crystalline coumarin salt. Formation of this derivative confirms a vital intermediate in the mechanism of the reaction. Salicylaldehyde, suitably protected, reacts with methyl acrylate to afford a novel coumarin not unlike the vasodilator chromonar.

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页码：2807 / 2815

页数：9

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