Glyoxal Formation and Its Role in Endogenous Oxalate Synthesis

被引：79

作者：

Lange, Jessica N. ^{[1
]}

Wood, Kyle D. ^{[1
]}

Knight, John ^{[1
]}

Assimos, Dean G. ^{[1
]}

Holmes, Ross P. ^{[1
]}

机构：

[1] Wake Forest Univ, Med Ctr, Dept Urol, Med Ctr Blvd, Winston Salem, NC 27157 USA

来源：

ADVANCES IN UROLOGY | 2012年 / 2012卷

关键词：

D O I：

10.1155/2012/819202

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Calcium oxalate kidney stones are a common condition affecting many people in the United States. The concentration of oxalate in urine is a major risk factor for stone formation. There is evidence that glyoxal metabolism may be an important contributor to urinary oxalate excretion. Endogenous sources of glyoxal include the catabolism of carbohydrates, proteins, and fats. Here, we review all the known sources of glyoxal as well as its relationship to oxalate synthesis and crystal formation.

引用

页数：5

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