Potential benefits of vitamin D for patients with systemic lupus erythematosus

被引：35

作者：

Singh, Abha ^{[1
]}

Kamen, Diane L. ^{[1
]}

机构：

[1] Med Univ South Carolina, Div Rheumatol & Immunol, Charleston, SC 29425 USA

来源：

DERMATO-ENDOCRINOLOGY | 2012年 / 4卷 / 02期

基金：

美国国家卫生研究院;

关键词：

systemic lupus erythematosits vitamin D; autoimmune disease; review;

D O I：

10.4161/derm.20443

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Systemic lupus erythematosus (SLE) is a Complex MUlti-system autoimmune disease. Vitamin D deficiency has been proposed as an environmental trigger of disease onset and as a contributor to increased SLE activity. SLE patients are prone to develop vitanlin D deficiency because of photosensitivity leading to sun avoidance and other sun protective measures. The impact of vitamin D on immune function previously seen in vitro and in cross-sectional studies has now been shown dies strengthening the evidence thatprospective human ate that there is a connection between SLE and vitamin D status. This review describes the role of vitamin D on immune function, prevalence of vitamin D deficiency in patients with SLE, identify risk factors for deficiency describe the consequences of deficiency in SLE patients, and review current vitamin D recommendations for patients with SLE.

引用

页码：146 / 151

页数：6

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