TNFα release by the nonfat cells of human adipose tissue

被引：0
作者：
J N Fain
S W Bahouth
A K Madan
机构：
[1] College of Medicine,Department of Molecular Sciences
[2] University of Tennessee Health Science Center,Department of Pharmacology
[3] College of Medicine,Department of Surgery
[4] University of Tennessee Health Science Center,undefined
[5] College of Medicine,undefined
[6] University of Tennessee Health Science Center,undefined
来源：
International Journal of Obesity | 2004年 / 28卷
关键词：
adiponectin; IL-6; HGF; PAI-1; leptin; niflumic acid; lipopolysaccharride;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
OBJECTIVE: The primary aim was to investigate the relative importance of the adipocytes vs the nonfat cells present in human adipose tissue with respect to release of immunoreactive tumor necrosis factor-α (TNFα). The second aim was to examine the correlation between body mass index (BMI) and the subsequent release of adiponectin and TNFα by explants of human subcutaneous and visceral adipose tissue incubated in primary culture for 48 h.
引用
收藏
页码：616 / 622
页数：6
相关论文
共 178 条
[1]  
Hotamisligil GS(1995)Increased adipose tissue expression of tumor necrosis factor- J Clin Invest 95 2409-2415
[2]  
Arner P(2002) in human obesity and insulin resistance Obes Res 10 499-506
[3]  
Caro JF(1998)Opposite regulation of plasma interleukin-8 and tumor necrosis factor- J Clin Endocrinol Metab 83 2907-2910
[4]  
Atkinson RL(2000) by weight loss Int J Obes Relat Metab Disord 24 1392-1395
[5]  
Spiegelman BM(2002)Tumor necrosis factor-a in sera of obese patients: fall with weight loss Int J Obes Relat Metab Disord 26 659-662
[6]  
Bruun JM(1999)Serum concentrations of TNF- Arterioscler Thromb Vasc Biol 19 972-978
[7]  
Pedersen SB(2001) and soluble TNF- J Pediatr Endocrinol Metab 14 543-547
[8]  
Kristensen K(2001) receptors in obesity Horm Res 55 57-64
[9]  
Richelsen B(2001)Markers of chronic inflammation and obesity: a prospective study on the reversibility of this association in middle-aged women undergoing weight loss by surgical intervention Am J Physiol Endocrinol Metab 280 E745-E751
[10]  
Dandona P(1995)C-reactive protein in healthy subjects: associations with obesity, insulin resistance and endothelial dysfunction: a potential role for cytokines originating from adipose tissue? J Clin Invest 95 2111-2119
12345678910