The evolving role of medical therapy for chronic stable angina

被引：3

作者：

Eid F. ^{[1
]}

Boden W.E. ^{[1
]}

机构：

[1] Division of Cardiology, Buffalo General Hospital, SUNY at Buffalo School of Medicine, Buffalo, NY 14203

来源：

Current Cardiology Reports | 2008年 / 10卷 / 4期

关键词：

Percutaneous Coronary Interven; Varenicline; Bare Metal Stents; Stable Coronary Artery Disease; Ranolazine;

D O I：

10.1007/s11886-008-0044-y

中图分类号：

学科分类号：

摘要：

The management of chronic stable angina has undergone considerable evolution over the past two decades. This article highlights the need for a comprehensive approach to management that includes carefully identifying cardiac risk factors, using therapeutic lifestyle interventions, aggressive, multifaceted medical therapy, and judiciously using myocardial revascularization. For patients whose ischemia cannot be optimally controlled with traditional anti-ischemic agents, a novel antianginal and anti-ischemic agent (ie, ranolazine) has promise in reducing refractory ischemia as add-on therapy. This article discusses the role of coronary artery bypass graft surgery and percutaneous coronary intervention (PCI) in managing chronic stable angina patients and the clinical implications of the COURAGE (Clinical Outcomes Utilizing Revascularization and Aggressive drug Evaluation) trial. The combined use of a focal" approach (PCI to treat the culprit stenosis) and a "systemic" approach (lifestyle intervention and aggressive pharmacotherapy) may afford the best event-free survival and clinical outcomes in patients with stable angina. © Current Medicine Group LLC 2008."

引用

页码：263 / 271

页数：8

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