Recurrent disseminated retinoblastoma in a 7-year-old girl treated successfully by high-dose chemotherapy and CD34-selected autologous peripheral blood stem cell transplantation

被引：0
作者：
H Hertzberg
B Kremens
I Velten
JD Beck
J Greil
机构：
[1] University Hospital for Children and Adolescents,
[2] Friedrich-Alexander University of Erlangen-Nürnberg,undefined
[3] University Hospital for Children and Adolescents,undefined
[4] University of Essen,undefined
[5] University Hospital of Ophthalmology,undefined
[6] Friedrich-Alexander University of Erlangen-Nürnberg,undefined
[7] University Hospital for Children,undefined
[8] University of Tübingen,undefined
来源：
Bone Marrow Transplantation | 2001年 / 27卷
关键词：
metastatic retinoblastoma; haematogenous metastasis; high-dose chemotherapy; autologous stem cell transplantation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A localized retinoblastoma of the left eye in a 7-year-old girl, was treated by enucleation. She received no additional therapy. Four months later, metastases of retinoblastoma in the lymph nodes, bone and bone marrow were diagnosed. Relapse chemotherapy consisting of three courses of vincristine, cyclophosphamide, etoposide and carboplatin led to a second complete remission. Subsequent high-dose chemotherapy with thiotepa, etoposide and carboplatin and autologous stem cell transplantation with CD34-selected stem cells were successful, with no adverse effects. No radiotherapy was given and the girl remains in continuous second remission with a follow-up of more than 4 years. Bone Marrow Transplantation (2001) 27, 653–655.
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页码：653 / 655
页数：2
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