The treatment of Wilms' tumour: results of the United Kingdom Children's Cancer Study Group (UKCCSG) second Wilms' tumour study

被引：0

作者：

C Mitchell

P Morris Jones

A Kelsey

G M Vujanic

B Marsden

R Shannon

P Gornall

C Owens

R Taylor

J Imeson

H Middleton

J Pritchard

机构：

[1] Paediatric Oncology,Department of Histopathology

[2] Oxford Radcliffe Hospital,Department of Surgery

[3] Royal Manchester Children's Hospital,Department of Radiology

[4] University of Wales College of Medicine,undefined

[5] Paediatric Oncology,undefined

[6] Leicester Royal Infirmary,undefined

[7] Birmingham Children's Hospital,undefined

[8] Great Ormond Street Hospital for Children,undefined

[9] Cookridge Hospital,undefined

[10] UKCCSG Data Centre,undefined

[11] University of Leicester,undefined

[12] Institute of Child Health,undefined

来源：

British Journal of Cancer | 2000年 / 83卷

关键词：

Wilms'; tumour; treatment; chemotherapy; radiotherapy; childhood cancer;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The aims of the UKW2 study were: (1) to further refine treatment for stage I and II favourable histology (FH) patients; (2) to consolidate the UKW1 results for stage III FH patients; (3) to improve the outlook for patients with inoperable primary tumours and those patients with stage IV and unfavourable histology disease. Treatment consisted of primary nephrectomy, wherever possible, followed by chemotherapy and radiotherapy, as dictated by stage and histology. Treatment was refined successfully for stage I and II FH patients. The 4-year event-free survival for these two groups was 94% and 91%, respectively. Stage III FH patients had a 4-year event free survival of 84%. The outlook for patients with clear cell sarcoma of the kidney is as good as for patients with favourable histology, whilst that for patients with anaplastic or rhabdoid variants remains poor. The outlook for the majority of children with Wilms’ tumour is now excellent. © 2000 Cancer Research Campaign

引用

页码：602 / 608

页数：6

共 150 条

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