Enhancement of multiple cranial and spinal nerves in vanishing white matter: expanding the differential diagnosis

被引：0
|
作者：
Thomas Jose Eluvathingal Muttikkal
Denia Ramirez Montealegre
Julie Ann Matsumoto
机构：
[1] University of Virginia Medical Center,Department of Radiology and Medical Imaging
[2] University of Virginia Medical Center,Pediatric Neurology Division, Department of Neurology
来源：
Pediatric Radiology | 2018年 / 48卷
关键词：
Brain; Child; Cranial nerves; Leukodystrophy; Magnetic resonance imaging; Spinal nerves; Vanishing white matter;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Abnormal cranial or spinal nerve contrast enhancement on MRI in cases of suspected pediatric leukodystrophy is recognized as an important clue to the diagnosis of either metachromatic leukodystrophy or globoid cell leukodystrophy (Krabbe disease). We report a case of genetically confirmed childhood vanishing white matter with enhancement of multiple cranial and spinal nerves in addition to the more typical intracranial findings. This case expands the limited differential diagnosis of cranial nerve or spinal nerve enhancement in cases of suspected leukodystrophy and may aid in more efficient work-up and earlier diagnosis of vanishing white matter.
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页码：437 / 442
页数：5
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