Synthesis and Analgesic Activity of Substituted 4-(Het)aryl-4-oxo-2-thienylaminobut-2-enoic Acids

被引：0
作者：
S. A. Shipilovskikh
R. R. Makhmudov
D. Yu. Lupach
P. T. Pavlov
E. V. Babushkina
A. E. Rubtsov
机构：
[1] State Higher Professional Educational Institution “Perm State National Research University”,Natural Sciences Institute
[2] Federal State Higher Professional Educational Institution “Perm State National Research University”,undefined
[3] OOO Lakton,undefined
[4] State Scientific Institution “Federal Scientific Center for Medical-Prophylactic Population Health Risk Management Technologies”,undefined
来源：
Pharmaceutical Chemistry Journal | 2013年 / 47卷
关键词：
substituted 4-aryl-4-oxo-2-thienylaminobut-2-enoic acids; synthesis; analgesic activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A series of 4-aryl-4-oxo-2-thienylaminobut-2-enoic acids was synthesized by interaction of 4-aryl-2-hydroxy-4-oxobut-2-enoic acids with Gewald 2-aminothiophenes. All the compounds synthesized were found to have analgesic activity at or above the levels of the reference compounds.
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页码：366 / 370
页数：4
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