Molecular Biomarkers in the Cerebrospinal Fluid in Multiple Sclerosis

被引：0
作者：
Shedko E.D. [1 ]
Tyumentseva M.A. [1 ]
机构：
[1] Central Research Institute of Epidemiology, Russian Federal Service for Surveillance of Consumer Rights Protection and Human Wellbeing (Rospotrebnadzor), Moscow
来源：
Neuroscience and Behavioral Physiology | 2020年 / 50卷 / 5期
关键词：
autoimmune diseases; biomarkers; cerebrospinal fluid; multiple sclerosis;
D O I：
10.1007/s11055-020-00932-z
中图分类号：
学科分类号：
摘要：
Multiple sclerosis (MS) is a chronic autoimmune disease affecting the spinal cord and brain. Detection of the disease at its initial stages is a difficult task as the causes and mechanisms of the manifestations of the disease remain unclear. Diagnosis of MS is a complex process. Studies of the molecular mechanisms of the disease and the search for biomarkers are among the key directions in the diagnosis of the disease. This review addresses potential biomarkers for multiple sclerosis detected in the cerebrospinal fluid. © 2020, Springer Science+Business Media, LLC, part of Springer Nature.
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页码：527 / 533
页数：6
相关论文
共 80 条
  • [1] Goldenberg M.M., Multiple sclerosis review, Pharmac. Ther., 37, 3, pp. 175-184, (2012)
  • [2] Loma I., Heyman R., Multiple sclerosis: pathogenesis and treatment, Curr. Neuropharmacol., 9, 3, pp. 409-416, (2011)
  • [3] Katdare A., Ursekar M., Systematic imaging review: Multiple sclerosis, Ann. Ind. Acad. Neurol., 18, pp. 24-29, (2015)
  • [4] Sajja B.R., Wolinsky J.S., Narayana P.A., Proton magnetic resonance spectroscopy in multiple sclerosis, Neuroimaging Clin. N. Am., 19, 1, pp. 45-58, (2009)
  • [5] Gourraud P.A., McElroy J.P., Caillier S.J., Et al., Aggregation of multiple sclerosis genetic risk variants in multiple and single case families, Ann. Neurol., 69, 1, pp. 65-74, (2011)
  • [6] Sundstrom P., Juto P., Wadell G., Et al., An altered immune response to Epstein–Barr virus in multiple sclerosis: A prospective study, Neurology, 62, pp. 2277-2282, (2004)
  • [7] Nielsen J.M., Korteweg T., Barkhof F., Et al., Overdiagnosis of multiple sclerosis and magnetic resonance imaging criteria, Ann. Neurol., 58, pp. 781-783, (2005)
  • [8] Miller D., Barkhof F., Montalban X., Et al., Clinically isolated syndromes suggestive of multiple sclerosis. Part I: Natural history, pathogenesis, diagnosis, and prognosis, Lancet Neurol., 4, pp. 281-288, (2005)
  • [9] Lassmann H., Bruck W., Lucchinetti C.F., The immunopathology of multiple sclerosis: an overview, Brain Pathol., 17, 2, pp. 210-218, (2007)
  • [10] Polman C.H., Reingold S.C., Banwell B., Et al., Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria, Ann. Neurol., 69, 2, pp. 292-302, (2011)
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