Telomere Structure, Function, and Maintenance in Plants

被引：0
作者：
Mi Kyung Kim
Woo Taek Kim
机构：
[1] Yonsei University,Department of Systems Biology, College of Life Science
来源：
Journal of Plant Biology | 2018年 / 61卷
关键词：
Genome integrity; Telomere; Telomerase; Telomeric binding protein;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Telomeres in eukaryotes comprise specific repetitive DNA sequences and binding proteins. Since their absence results in chromosomal end fusions and gene deletions, they are considered critical for genomic stability. In plants, as in yeasts and mammals, telomeres are essential for normal development and differentiation. Despite recent discoveries concerning plant telomeres, many questions remain about the mechanism of telomere homeostasis in plants. In this review, we summarize the roles of telomeres and telomerasebinding proteins in plant biology and explain how the length of a plant telomere is regulated.
引用
收藏
页码：131 / 136
页数：5
相关论文
共 279 条
  • [1] Amiard S(2011)Arabidopsis ATM and ATR kinases prevent propagation of genome damage caused by telomere dysfunction Plant Cell 23 4254-4265
  • [2] Depeiges A(2012)Human Rap1 interacts directly with telomeric DNA and regulates TRF2 localization at the telomere J Biol Chem 287 41583-41594
  • [3] Allain E(2001)Pot1, the putative telomere end-binding protein in fission yeast and humans Science 292 1171-1175
  • [4] White CI(1997)Telomere shortening and tumor formation by mouse cells lacking telomerase RNA Cell 91 25-34
  • [5] Gallego ME(1997)Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2 Nat Genet 17 231-235
  • [6] Arat NO(1995)Telomere elongation in immortal human cells without detectable telomerase activity EMBO J 14 4240-4248
  • [7] Griffith JD(2005)A human cell line that maintains telomeres in the absence of telomerase and of key markers of ALT Oncogene 24 7893-78901
  • [8] Baumann P(2003)Telomere looping in P. sativum (common garden pea) Plant J 36 271-279
  • [9] Cech TR(2005)How the human telomeric proteins TRF1 and TRF2 recognize telomeric DNA: a view from high-resolution crystal structures EMBO Rep 6 39-45
  • [10] Blasco MA(2005)Shelterin: the protein complex that shapes and safeguards human telomeres Genes Dev 19 2100-2110
12345678910