SWI/SNF complex gene variations are associated with a higher tumor mutational burden and a better response to immune checkpoint inhibitor treatment: a pan-cancer analysis of next-generation sequencing data corresponding to 4591 cases

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作者
Yue Li
Xinhua Yang
Weijie Zhu
Yuxia Xu
Jiangjun Ma
Caiyun He
Fang Wang
机构
[1] Sun Yat-Sen University Cancer Center,Department of Molecular Diagnostics, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine
来源
Cancer Cell International | / 22卷
关键词
SWI/SNF complex genes; Mutational landscape; Tumor mutational burden; Microsatellite instability; Immune checkpoint inhibitors; Synthetic lethality;
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