Nocturnal desaturations in COPD: Still an open question?

被引：0
|
作者：
Braghiroli A. [1 ,2 ]
机构：
[1] Salvatore Maugeri Foundation, I.R.C.C.S., Scientific Institute of Veruno, Veruno
[2] Salvatore Maugeri Foundation, Centro Medico, Veruno
来源：
Sleep and Breathing | 2002年 / 6卷 / 1期
关键词：
COPD; Long-term oxygen therapy; Sleep desaturations;
D O I：
10.1007/s11325-002-0025-0
中图分类号：
学科分类号：
摘要：
The relevance of sleep oxyhemoglobin desaturations in COPD patients is still a matter of debate. The best definition for clinical outcomes is the occurrence of episodes lasting at least 5 minutes and reaching SaO2 levels less than or equal to 85%. Focusing on longer and milder episodes (at least 30% of the night with SaO2 < 90%) did not provide clinical relevance. One possible consequence of desaturation episodes could be a worsening of pulmonary hemodynamics, but O2 dips could just be a marker of a mechanical derangement associated with a worse prognosis. Data confirming the association of these episodes with the clinical type of COPD and with inflammatory mediator modulation are still lacking.
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页码：25 / 26
页数：1
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