New diterpenes from Nigella damascena seeds and their antiviral activities against herpes simplex virus type-1

被引：0

作者：

Keiko Ogawa

Seikou Nakamura

Kohei Hosokawa

Hanako Ishimaru

Natsuki Saito

Kaori Ryu

Masahiro Fujimuro

Souichi Nakashima

Hisashi Matsuda

机构：

[1] Kyoto Pharmaceutical University,Department of Pharmacognosy

[2] Misasagi,undefined

来源：

Journal of Natural Medicines | 2018年 / 72卷

关键词：

Ranunculaceae; Diterpene; Antiviral activity; HSV-1;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Nigella species are rich source of dolabellane diterpenes. During our study of Nigella species, new dolabellane diterpenes, damasterpenes V–VIII were isolated. The structural determination of new compounds damasterpenes V–VIII is described with consideration of their absolute configurations. The antiviral activities against herpes simplex virus type-1 of the isolated compounds and their derivatives are also evaluated. Damasterpene V (inhibition 35.0%) and 2-phenylacetyl 13-benzoyl damasterpenol (32.0%) showed significant antiviral activity at 10 μM.

引用

页码：439 / 447

页数：8

共 50 条

[21] Plant extracts antiviral activity against Herpes simplex virus type 1 and African swine fever virus
Silva, O
Barbosa, S
Diniz, A
Valdeira, ML
Gomes, E
INTERNATIONAL JOURNAL OF PHARMACOGNOSY, 1997, 35 (01): : 12 - 16
[22] ANTIVIRAL ACTIVITY OF TRICHOTHECENE MYCOTOXINS (DEOXYNIVALENOL, FUSARENON-X, AND NIVALENOL) AGAINST HERPES-SIMPLEX VIRUS TYPE-1 AND TYPE-2
TANI, N
DOHI, Y
ONJI, Y
YONEMASU, K
MICROBIOLOGY AND IMMUNOLOGY, 1995, 39 (08) : 635 - 637
[23] Antiviral activities of Boletus edulis, Pleurotus ostreatus and Lentinus edodes extracts and polysaccharide fractions against Herpes simplex virus type 1
Santoyo, Susana
Cristina Ramirez-Anguiano, Ana
Aldars-Garcia, Laila
Reglero, Guillermo
Soler-Rivas, Cristina
JOURNAL OF FOOD AND NUTRITION RESEARCH, 2012, 51 (04): : 225 - 235
[24] Nostoc muscorum is a novel source of microalgal lectins with potent antiviral activity against herpes simplex type-1
Saad, Mabroka H.
Sidkey, Nagwa M.
Khan, Rizwan Hasan
El-Fakharany, Esmail M.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, 210 : 415 - 429
[25] Importance of herpes simplex virus type-1 (HSV-1) in primary genital herpes
Nieuwenhuis, RF
van Doornum, GJJ
Mulder, PGH
Neumann, HAM
van der Meijden, WI
ACTA DERMATO-VENEREOLOGICA, 2006, 86 (02) : 129 - 134
[26] Nanoparticles: A Promising Treatment for Herpes Simplex Virus Type-1 Infections
Ahmadi, Mahsa
Bolourchi, Negin
Rezaei, Zeinab
Badmasti, Farzad
Shafiei, Morvarid
MEDITERRANEAN JOURNAL OF INFECTION MICROBES AND ANTIMICROBIALS, 2021, 10
[27] Antiviral activity of Phoenix dactylifera extracts against herpes simplex virus type 1: an animal study
Allahyari S.
Pakbin B.
Amani Z.
Mahmoudi R.
Hamidiyan G.
Peymani A.
Qajarbeygi P.
Mousavi S.
Comparative Clinical Pathology, 2021, 30 (6) : 945 - 951
[28] Nonneutralizing antibody against the glycoprotein K of herpes simplex virus type-1 exacerbates herpes simplex virus type-1-induced corneal scarring in various virus mouse strain combinations
Ghiasi, H
Cai, S
Slanina, S
Nesburn, AB
Wechsler, SL
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1997, 38 (06) : 1213 - 1221
[29] Antiviral Activity of Red Propolis Against Herpes Simplex Virus-1
Negri, Giuseppina
Duarte-Almeida, Joaquim Mauricio
Figueiredo, Cristina Adelaide
Toledo-Piza, Ana Rita de
Tonelli, Flavia Cristina Policarpo
Barbosa, Tamyris Fernanda
Mendonca, Ronaldo Zucatelli
BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2024, 60
[30] The Effects of the Diterpenes Isolated from the Brazilian Brown Algae Dictyota pfaffii and Dictyota menstrualis against the Herpes Simplex Type-1 Replicative Cycle
Abrantes, Juliana L.
Barbosa, Jussara
Cavalcanti, Diana
Pereira, Renato C.
Fontes, Carlos Frederico L.
Teixeira, Valeria L.
Souza, Thiago Moreno L.
Paixao, Izabel C. P.
PLANTA MEDICA, 2010, 76 (04) : 339 - 344

← 1 2 3 4 5 →