Synthesis of 14C-radioactively labeled derivatives of gossypol and the study of their pharmacokinetics

被引:0
|
作者
Sumin V.I. [1 ]
Ismailov A.I. [1 ]
Baram N.I. [1 ]
机构
[1] A. S. Sadykov Inst. of Bioorg. Chem., Acad. Sci. of the Rep. of Uzbekistan, Tashkent
关键词
Organic Chemistry; Gossypol;
D O I
10.1007/BF02249630
中图分类号
学科分类号
摘要
The method of obtaining radioactively labeled 14C-gossypol-acetic add has been improved: from it have been synthesized 14C-derivatives of gossypol and their complexes with N-polyvinylpyrrolidone. A comparative study has been made of the pharmacokinetics of batriden, megosin, and their water-soluble complexes.
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页码:636 / 641
页数:5
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  • [1] Synthesis of 14C-radioactively labeled samples of batriden
    Sumin, VN
    Sakhibov, AD
    Baram, NI
    Ismailov, AI
    CHEMISTRY OF NATURAL COMPOUNDS, 1999, 35 (02) : 165 - 167
  • [2] Synthesis of14C-radioactively labeled samples of batriden
    V. N. Sumin
    A. D. Sakhibov
    N. I. Baram
    A. I. Ismailov
    Chemistry of Natural Compounds, 1999, 35 : 165 - 167