Impact of the peroxisome proliferator activated receptor-γ coactivator-1β (PGC-1β) Ala203Pro polymorphism on in vivo metabolism, PGC-1β expression and fibre type composition in human skeletal muscle

[1] Puigserver P(2003)Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha): transcriptional coactivator and metabolic regulator Endocr Rev 24 78-90

[2] Spiegelman BM(2003)PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes Nat Genet 34 267-273

[3] Mootha VK(2003)Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: potential role of PGC1 and NRF1 Proc Natl Acad Sci USA 100 8466-8471

[4] Lindgren CM(2001)Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus Diabetologia 44 2220-2226

[5] Eriksson KF(2004)Multiple environmental and genetic factors influence skeletal muscle PGC-1alpha and PGC-1beta gene expression in twins J Clin Invest 114 1518-1526

[6] Patti ME(2005)Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity J Med Genet 42 402-407

[7] Butte AJ(2007)The transcriptional coactivator PGC-1beta drives the formation of oxidative type IIX fibers in skeletal muscle Cell Metab 5 35-46

[8] Crunkhorn S(2006)PGC-1alpha and PGC-1beta have both similar and distinct effects on myofiber switching toward an oxidative phenotype Am J Physiol Endocrinol Metab 291 E807-E816

[9] Ek J(2006)Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance PLoS Biol 4 e369-130

[10] Andersen G(1986)Longitudinal data analysis for discrete and continuous outcomes Biometrics 42 121-68

[1] Puigserver P(2003)Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha): transcriptional coactivator and metabolic regulator Endocr Rev 24 78-90

[2] Spiegelman BM(2003)PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes Nat Genet 34 267-273

[3] Mootha VK(2003)Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: potential role of PGC1 and NRF1 Proc Natl Acad Sci USA 100 8466-8471

[4] Lindgren CM(2001)Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus Diabetologia 44 2220-2226

[5] Eriksson KF(2004)Multiple environmental and genetic factors influence skeletal muscle PGC-1alpha and PGC-1beta gene expression in twins J Clin Invest 114 1518-1526

[6] Patti ME(2005)Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity J Med Genet 42 402-407

[7] Butte AJ(2007)The transcriptional coactivator PGC-1beta drives the formation of oxidative type IIX fibers in skeletal muscle Cell Metab 5 35-46

[8] Crunkhorn S(2006)PGC-1alpha and PGC-1beta have both similar and distinct effects on myofiber switching toward an oxidative phenotype Am J Physiol Endocrinol Metab 291 E807-E816

[9] Ek J(2006)Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance PLoS Biol 4 e369-130

[10] Andersen G(1986)Longitudinal data analysis for discrete and continuous outcomes Biometrics 42 121-68