Future directions in the prevention of prostate cancer

被引：0
作者：
Ian M. Thompson
April B. Cabang
Michael J. Wargovich
机构：
[1] Cancer Therapy and Research Center,
[2] University of Texas Health Science Center at San Antonio,undefined
来源：
Nature Reviews Clinical Oncology | 2014年 / 11卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Chemoprevention has been increasingly explored to mitigate the global burden of prostate cancer and the overtreatment of indolent disease that has arisen in the prostate-specific antigen (PSA) screening eraPreclinical and epidemiological evidence suggested that selenium and α-tocopherol (vitamin E) might reduce the risk of prostate cancerA large trial found vitamin E to significantly increase the risk of prostate cancer and selenium to have no effect on riskThe strongest evidence supports the use of 5α-reductase inhibitors for prostate cancer prevention, with recent data showing that the risk reduction with these agents is 30%
引用
收藏
页码：49 / 60
页数：11
相关论文
共 283 条
[61]  
Mayor A(2013)Curcumin inhibits prostate cancer metastasis Mol. Pharm. 10 2676-1527
[62]  
Tardivel A(2007) by targeting the inflammatory cytokines CXCL1 and -2 Adv. Exp. Med. Biol. 595 453-4530
[63]  
Tschopp J(2012)Synergistic interaction of paclitaxel and curcumin with cyclodextrin polymer complexation in human cancer cells Cancer Chemother. Pharmacol. 69 679-682
[64]  
Mimeault M(2009)Pharmacokinetics and pharmacodynamics of curcumin Eur. J. Pharm. Sci. 37 223-510
[65]  
Batra SK(2012)Enhancement of curcumin oral absorption and pharmacokinetics of curcuminoids and curcumin metabolites in mice Asian Pac. J. Trop. Biomed. 2 841-1953
[66]  
Kristal AR(2011)Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer Food Funct. 2 373-2142
[67]  
Colli JL(2012)Preparation and characterization of curcumin-piperine dual drug loaded nanoparticles J. Agric. Food Chem. 60 5373-122
[68]  
Amling CL(2013)Structure of modified e-polylysine micelles and their application in improving cellular antioxidant activity of curcuminoids Oncol. Rep. 29 1983-453
[69]  
Khan N(2011)Improving the oral bioavailability of curcumin using novel organogel-based nanoemulsions Int. J. Oncol. 39 1521-473
[70]  
Afaq F(2006)Epigallocatechin gallate promotes p53 accumulation and activity via the inhibition of MDM2-mediated p53 ubiquitination in human lung cancer cells Cancer Res. 66 4525-672
234567891011