Treatment of Psychosis in Parkinson’s DiseaseSafety Considerations

被引：0
作者：
Hubert H. Fernandez
Martha E. Trieschmann
Joseph H. Friedman
机构：
[1] Brown University School of Medicine,Department of Clinical Neurosciences
来源：
Drug Safety | 2003年 / 26卷
关键词：
Clozapine; Risperidone; Olanzapine; Quetiapine; Ziprasidone;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Psychosis only rarely occurs in patients with untreated Parkinson’s disease. Much more commonly, psychosis is induced by drug therapy for Parkinson’s disease and is the strongest known risk factor for nursing home placement. Delusions are less frequent than hallucinations, but are more concerning as they are often paranoid in nature. Treatment begins with a search for correctable infectious, toxic, and metabolic aetiologies. If symptoms persist, anti-Parkinson’s disease medications are slowly reduced. However, withdrawal of these drugs usually worsens parkinsonism and is often not tolerated. Certain atypical antipsychotics can be used to treat psychosis without compromising motor function.
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页码：643 / 659
页数：16
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