Pollen-related food allergy: cloning and immunological analysis of isoforms and mutants of Mal d 1, the major apple allergen, and Bet v 1, the major birch pollen allergen

被引：0
|
作者：
D.Y. Son
S. Scheurer
A. Hoffmann
D. Haustein
S. Vieths
机构：
[1] Paul-Ehrlich-Institut,
[2] Department of Allergology,undefined
[3] Paul-Ehrlich-Str. 51–59,undefined
[4] D.-63225 Langen,undefined
[5] Germany,undefined
来源：
European Journal of Nutrition | 1999年 / 38卷
关键词：
Key words Apple allergen – epitopes – IgE – isoforms –, mutants – strains;
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学科分类号：
摘要：
Background: Mal d 1, the major apple allergen, cross-reacts with IgE specific for the major birch pollen allergen, Bet v 1, and is responsible for birch pollen related food allergy to apple. Isoforms of Bet v 1 showing minor sequence variations display different binding capacitiy for specific IgE antibodies from allergic patients. Moreover, strain-dependent variation of allergenicity has been reported for apples.
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页码：201 / 215
页数：14
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