DNA nanowire translocation phenomena in nanopores

被引：0
作者：
Lei Chen
A. T. Conlisk
机构：
[1] The Ohio State University,Department of Mechanical Engineering
来源：
Biomedical Microdevices | 2010年 / 12卷
关键词：
Nanopore sequencing; DNA translocation; Hydrodynamic modeling; Electroosmotic flow;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
One recent application of nanopores is to use them as detectors and analyzers for fast DNA sequencing. To better understand the DNA electrokinetic transport through a nanopore, a hydrodynamic model is developed to investigate the flow field, the resistive forces acting on the DNA, the DNA velocity and the ionic current through the nanopore. The numerical results reveal the relation between the DNA velocity and various parameters such as nanopore surface charge and solution concentration. The model is validated by comparing the numerical results with the experimental data for both DNA velocity and ionic current through the nanopore.
引用
收藏
页码：235 / 245
页数：10
相关论文
共 50 条
[21]   Translocation of Precision Polymers through Biological Nanopores [J].
Boukhet, Mordjane ;
Konig, Niklas Felix ;
Al Ouahabi, Abdelaziz ;
Baaken, Gerhard ;
Lutz, Jean-Francois ;
Behrends, Jan C. .
MACROMOLECULAR RAPID COMMUNICATIONS, 2017, 38 (24)
[22]   Dynamics of polymer translocation through kinked nanopores [J].
Wang, Junfang ;
Wang, Yilin ;
Luo, Kaifu .
JOURNAL OF CHEMICAL PHYSICS, 2015, 142 (08)
[23]   Hydrodynamic Slip on DNA Observed by Optical Tweezers-Controlled Translocation Experiments with Solid-State and Lipid-Coated Nanopores [J].
Galla, Lukas ;
Meyer, Andreas J. ;
Spiering, Andre ;
Sischka, Andy ;
Mayer, Michael ;
Hall, Adam R. ;
Reimann, Peter ;
Anselmetti, Dario .
NANO LETTERS, 2014, 14 (07) :4176-4182
[24]   Nanoparticle Translocation through Conical Nanopores: A Finite Element Study of Electrokinetic Transport [J].
Rempfer, Georg ;
Ehrhardt, Sascha ;
Holm, Christian ;
de Graaf, Joost .
MACROMOLECULAR THEORY AND SIMULATIONS, 2017, 26 (01)
[25]   Fast Translocation of Proteins through Solid State Nanopores [J].
Plesa, Calin ;
Kowalczyk, Stefan W. ;
Zinsmeester, Ruben ;
Grosberg, Alexander Y. ;
Rabin, Yitzhak ;
Dekker, Cees .
NANO LETTERS, 2013, 13 (02) :658-663
[26]   Brownian Motion Paving the Way for Molecular Translocation in Nanopores [J].
Lee, Won-Yong ;
Wen, Chenyu ;
Pham, Ngan Hoang ;
Khaksaran, Mohammad Hadi ;
Lee, Sang-Kwon ;
Zhang, Shi-Li .
SMALL METHODS, 2024, 8 (12)
[27]   On the Lubensky-Nelson Model of Polymer Translocation through Nanopores [J].
Reimann, Peter ;
Meyer, Andreas ;
Getfert, Sebastian .
BIOPHYSICAL JOURNAL, 2012, 103 (05) :889-897
[28]   The role of functionalization in the translocation of peptides through multilayer graphene nanopores [J].
Suresh, Hareesh ;
Haridasan, Navaneeth ;
Varghese, Binu ;
Sathian, Sarith P. .
JOURNAL OF CHEMICAL PHYSICS, 2025, 162 (06)
[29]   Dielectric Manipulation of Polymer Translocation Dynamics in Engineered Membrane Nanopores [J].
Buyukdagli, Sahin .
LANGMUIR, 2022, 38 (01) :122-131
[30]   Gate Manipulation of DNA Capture into Nanopores [J].
He, Yuhui ;
Tsutsui, Makusu ;
Fan, Chun ;
Taniguchi, Masateru ;
Kawai, Tomoji .
ACS NANO, 2011, 5 (10) :8391-8397
12345