DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity

[31] Boyd JT(1996)De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5)-methyltransferase Mol Cell Biol 16 4555-6369

[32] Chapman JD(2006)Combined DNA methyltransferase and histone deacetylase inhibition in the treatment of myeloid neoplasms Cancer Res 66 6361-3822

[33] Kim IA(2005)Valproic acid alters chromatin structure by regulation of chromatin modulation proteins Cancer Res 65 3815-64

[34] Shin JH(1991)The Influence of Chromatin Structure on the Frequency of Radiation-Induced DNA Strand Breaks - a Study Using Nuclear and Nucleoid Monolayers Radiat Res 126 58-244

[35] Kim IH(1989)Chromatin Decondensed by Acetylation Shows an Elevated Radiation Response Radiat Res 117 234-28181

[36] Kim JH(2002)An essential role for DNA methyltransferase DNMT3B in cancer cell survival J Biol Chem 277 28176-5868

[37] Kim JS(1998)DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139 J Biol Chem 273 5858-11304

[38] Wu HG(2006)Histone deacetylase (HDAC) inhibitor LBH589 increases duration of gamma-H2AX foci and confines HDAC4 to the cytoplasm in irradiated non-small cell lung cancer Cancer Res 66 11298-107

[39] Chie EK(1999)Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer Nat Genet 21 103-undefined

[40] Ha SW(undefined)undefined undefined undefined undefined-undefined

[31] Boyd JT(1996)De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5)-methyltransferase Mol Cell Biol 16 4555-6369

[32] Chapman JD(2006)Combined DNA methyltransferase and histone deacetylase inhibition in the treatment of myeloid neoplasms Cancer Res 66 6361-3822

[33] Kim IA(2005)Valproic acid alters chromatin structure by regulation of chromatin modulation proteins Cancer Res 65 3815-64

[34] Shin JH(1991)The Influence of Chromatin Structure on the Frequency of Radiation-Induced DNA Strand Breaks - a Study Using Nuclear and Nucleoid Monolayers Radiat Res 126 58-244

[35] Kim IH(1989)Chromatin Decondensed by Acetylation Shows an Elevated Radiation Response Radiat Res 117 234-28181

[36] Kim JH(2002)An essential role for DNA methyltransferase DNMT3B in cancer cell survival J Biol Chem 277 28176-5868

[37] Kim JS(1998)DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139 J Biol Chem 273 5858-11304

[38] Wu HG(2006)Histone deacetylase (HDAC) inhibitor LBH589 increases duration of gamma-H2AX foci and confines HDAC4 to the cytoplasm in irradiated non-small cell lung cancer Cancer Res 66 11298-107

[39] Chie EK(1999)Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer Nat Genet 21 103-undefined

[40] Ha SW(undefined)undefined undefined undefined undefined-undefined