DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity

[1] Robertson KD(2001)DNA methylation, methyltransferases, and cancer Oncogene 20 3139-3155

[2] Manoharan M(2007)Epigenetic targets in the diagnosis and treatment of prostate cancer Int Braz J Urol 33 11-18

[3] Ramachandran K(2007)Alteration of DNA methyltransferases contributes to 5'CpG methylation and poor prognosis in lung cancer Lung Cancer 55 205-213

[4] Soloway MS(1999)CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression Cancer Res 59 2302-2306

[5] Singal R(1980)Cellular differentiation, cytidine analogs and DNA methylation Cell 20 85-93

[6] Lin RK(2007)Epigenetic therapy in cancer: molecular background and clinical development of histone deacetylase and DNA methyltransferase inhibitors IDrugs 10 557-561

[7] Hsu HS(2009)Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead Int J Biochem Cell Biol 41 199-213

[8] Chang JW(2003)The role of DNA methylation in setting up chromatin structure during development Nat Genet 34 187-192

[9] Chen CY(2001)Chemical agents that promote chromatin compaction radiosensitize tumour cells Int J Radiat Biol 77 1033-1042

[10] Chen JT(2006)Histone deacetylase inhibitor-mediated radiosensitization of human cancer cells: class differences and the potential influence of p53 Clin Cancer Res 12 940-949

[1] Robertson KD(2001)DNA methylation, methyltransferases, and cancer Oncogene 20 3139-3155

[2] Manoharan M(2007)Epigenetic targets in the diagnosis and treatment of prostate cancer Int Braz J Urol 33 11-18

[3] Ramachandran K(2007)Alteration of DNA methyltransferases contributes to 5'CpG methylation and poor prognosis in lung cancer Lung Cancer 55 205-213

[4] Soloway MS(1999)CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression Cancer Res 59 2302-2306

[5] Singal R(1980)Cellular differentiation, cytidine analogs and DNA methylation Cell 20 85-93

[6] Lin RK(2007)Epigenetic therapy in cancer: molecular background and clinical development of histone deacetylase and DNA methyltransferase inhibitors IDrugs 10 557-561

[7] Hsu HS(2009)Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead Int J Biochem Cell Biol 41 199-213

[8] Chang JW(2003)The role of DNA methylation in setting up chromatin structure during development Nat Genet 34 187-192

[9] Chen CY(2001)Chemical agents that promote chromatin compaction radiosensitize tumour cells Int J Radiat Biol 77 1033-1042

[10] Chen JT(2006)Histone deacetylase inhibitor-mediated radiosensitization of human cancer cells: class differences and the potential influence of p53 Clin Cancer Res 12 940-949