Differential expression of matrix metalloproteinases and cyclooxygenases in synovial cells exposed to Borrelia burgdorferi

被引：0

作者：

S. K. Singh

H. Morbach

T. Nanki

C. Faber

V. Baar

H. J. Girschick

机构：

[1] University of Wuerzburg,Pediatric Rheumatology and Infectious Diseases, Children’s Hospital

[2] Tokyo Medical and Dental University,Department of Bioregulatory Medicine and Rheumatology

来源：

Inflammation Research | 2004年 / 53卷

关键词：

Inflammation; Metalloproteinases; Cyclooxygenases; Pathogen host interaction;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Objective and design: Lyme arthritis is characterized by strong inflammatory reactions probably due to the presence of Borrelia burgdorferi in the joint. It has been suggested that Borrelia adopts different molecular mechanisms that either can amplify the host’s inflammatory response or can suppress it. In the present study we analyzed the induction of matrix metalloproteinases (MMPs) and cyclooxygenases (COXs) in human synoviocytes exposed to different B. burgdorferi sensu stricto isolates (Geho and B31).

引用

页码：689 / 696

页数：7