A measured approach to managing the aortic root in patients with bicuspid aortic valve disease

被引：1
作者：
El-Hamamsy I. [1 ]
Yacoub M.H. [1 ]
机构：
[1] Harefield Heart Science Center, Middlesex UB9 6JH, Hill End Road, Harefield
来源：
Current Cardiology Reports | 2009年 / 11卷 / 2期
关键词：
Aortic Valve; Aortic Aneurysm; Aortic Dissection; Aortic Root; Aortic Valve Replacement;
D O I：
10.1007/s11886-009-0015-y
中图分类号：
学科分类号：
摘要：
Bicuspid (or bicommissural) aortic valve (BAV) is the most common cardiovascular malformation in humans, with a prevalence of 1% to 2% in the general population and a 2:1 male:female ratio. BAV is frequently associated with other cardiovascular malformations, including aortic root dilatation, which affects about 40% of individuals with BAVs and is thought to be associated with increased risk of dissection and/or rupture. Currently, no agreement exists about the optimal management of these patients. We review the pathophysiology and possible determinants of aortic disease associated with BAV, the natural history of aortic wall size progression, and suggest management strategies to prevent acute aortic events. © Current Medicine Group, LLC 2009.
引用
收藏
页码：94 / 100
页数：6
相关论文
共 65 条
  • [1] Roberts W.C., The congenitally bicuspid aortic valve. A study of 85 autopsy cases, Am J Cardiol, 26, pp. 72-83, (1970)
  • [2] Roberts W.C., Ko J.M., Frequency by decades of unicuspid, bicuspid, and tricuspid aortic valves in adults having isolated aortic valve replacement for aortic stenosis, with or without associated aortic regurgitation, Circulation, 111, pp. 920-925, (2005)
  • [3] Lewin M.B., Otto C.M., The bicuspid aortic valve: Adverse outcomes from infancy to old age, Circulation, 111, pp. 832-834, (2005)
  • [4] Brenner J.I., Berg K.A., Schneider D.S., Et al., Cardiac malformations in relatives of infants with hypoplastic left-heart syndrome, Am J Dis Child, 143, pp. 1492-1494, (1989)
  • [5] Roos-Hesselink J.W., Scholzel B.E., Heijdra R.J., Et al., Aortic valve and aortic arch pathology after coarctation repair, Heart, 89, pp. 1074-1077, (2003)
  • [6] Larson E.W., Edwards W.D., Risk factors for aortic dissection: A necropsy study of 161 cases, Am J Cardiol, 53, pp. 849-855, (1984)
  • [7] Roberts C.S., Roberts W.C., Dissection of the aorta associated with congenital malformation of the aortic valve, J Am Coll Cardiol, 17, pp. 712-716, (1991)
  • [8] Robicsek F., Thubrikar M.J., Cook J.W., Fowler B., The congenitally bicuspid aortic valve: How does it function? Why does it fail?, Ann Thorac Surg, 77, pp. 177-185, (2004)
  • [9] Yacoub M.H., Kilner P.J., Birks E.J., Misfeld M., The aortic outflow and root: A tale of dynamism and crosstalk, Ann Thorac Surg, 68, (1999)
  • [10] Della Corte A., Quarto C., Bancone C., Et al., Spatiotemporal patterns of smooth muscle cell changes in ascending aortic dilatation with bicuspid and tricuspid aortic valve stenosis: Focus on cell-matrix signaling, J Thorac Cardiovasc Surg, 135, 8-18, (2008)
1234567