Dynamics of mRNA entry into stress granules

被引：0

作者：

Chih-Yung Lee

Geraldine Seydoux

机构：

[1] Johns Hopkins University,Department of Molecular Biology and Genetics

来源：

Nature Cell Biology | 2019年 / 21卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Stressed eukaryotic cells store mRNAs in protein-rich condensates called stress granules. Using single-molecule tracking techniques to examine how mRNAs enter stress granules, a new study shows that mRNAs make transient contacts with the granule surface before stable association, and become largely immobile after entry.

引用

页码：116 / 117

页数：1

共 50 条

[21] Stress granules in cancer: Adaptive dynamics and therapeutic implications
Jia, Yunlu
Jia, Ruyin
Dai, Zhengfeng
Zhou, Jianbiao
Ruan, Jian
Chng, Weejoo
Cai, Zhen
Zhang, Xiaochen
ISCIENCE, 2024, 27 (08)
[22] Dynamic m6A methylation facilitates mRNA triaging to stress granules
Anders, Maximilian
Chelysheva, Irina
Goebel, Ingrid
Trenkner, Timo
Zhou, Jun
Mao, Yuanhui
Verzini, Silvia
Qian, Shu-Bing
Ignatova, Zoya
LIFE SCIENCE ALLIANCE, 2018, 1 (04)
[23] Staufen recruitment into stress granules does not affect early mRNA transport in oligodendrocytes
Thomas, MG
Tosar, LJM
Loschi, M
Pasquini, JM
Correale, J
Kindler, S
Boccaccio, GL
MOLECULAR BIOLOGY OF THE CELL, 2005, 16 (01) : 405 - 420
[24] Limited effects of m6A modification on mRNA partitioning into stress granules
Anthony Khong
Tyler Matheny
Thao Ngoc Huynh
Vincent Babl
Roy Parker
Nature Communications, 13
[25] Stress Granules and P-Bodies: An Insight into mRNA Translational Control and Decay
Roy, Raju
Rajyaguru, Purusharth I.
PROCEEDINGS OF THE INDIAN NATIONAL SCIENCE ACADEMY, 2018, 84 (02): : 479 - 491
[26] Limited effects of m6A modification on mRNA partitioning into stress granules
Khong, Anthony
Matheny, Tyler
Huynh, Thao Ngoc
Babl, Vincent
Parker, Roy
NATURE COMMUNICATIONS, 2022, 13 (01)
[27] mRNA with Mammalian Codon Bias Accumulates in Yeast Mutants with Constitutive Stress Granules
Kozlova, Natalia, V
Pichon, Chantal
Rahmouni, A. Rachid
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (04)
[28] The ribosome structure controls and directs mRNA entry, translocation and exit dynamics
Kurkcuoglu, Ozge
Doruker, Pemra
Sen, Taner Z.
Kloczkowski, Andrzej
Jernigan, Robert L.
PHYSICAL BIOLOGY, 2008, 5 (04)
[29] Nanoscale dynamics and localization of single endogenous mRNAs in stress granules
Sugawara, Ko
Uno, Shin-nosuke
Kamiya, Mako
Sakamoto, Akihiko
Urano, Yasuteru
Funatsu, Takashi
Okabe, Kohki
NUCLEIC ACIDS RESEARCH, 2024, 52 (15) : 8675 - 8686
[30] Stressful steps: Progress and challenges in understanding stress-induced mRNA condensation and accumulation in stress granules
Glauninger, Hendrik
Hickernell, Caitlin J. Wong
Bard, Jared A. M.
Drummond, D. Allan
MOLECULAR CELL, 2022, 82 (14) : 2544 - 2556

← 1 2 3 4 5 →