Enhancement of thioredoxin/glutaredoxin-mediated L-cysteine synthesis from S-sulfocysteine increases L-cysteine production in Escherichia coli

被引:0
作者
Takeshi Nakatani
Iwao Ohtsu
Gen Nonaka
Natthawut Wiriyathanawudhiwong
Susumu Morigasaki
Hiroshi Takagi
机构
[1] Nara Institute of Science and Technology,Graduate School of Biological Sciences
[2] Research Institute for Bioscience Products and Fine Chemicals,National Center for Genetic Engineering and Biotechnology
[3] National Science and Technology Development Agency,undefined
来源
Microbial Cell Factories | / 11卷
关键词
Thiosulfate pathway; L-cysteine; Redox enzyme; Sulfite reductase; -sulfocysteine;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 90 条
  • [1] Ohtsu I(2010)The L-cysteine/L-cystine shuttle system provides reducing equivalents to the periplasm in J Biol Chem 285 17479-17487
  • [2] Wiriyathanawudhiwong N(1967)Regulation of homoserine biosynthesis byL-cysteine, a terminal metabolite of a linked pathway Proc Natl Acad Sci USA 58 635-641
  • [3] Morigasaki S(2003)High levels of intracellular cysteine promote oxidative DNA damage by driving the Fenton reaction J Bacteriol 185 1942-1950
  • [4] Nakatani T(1998)Overproduction ofl-cysteine andl-cystine by Appl Environ Microbiol 64 1607-1611
  • [5] Kadokura H(2005) with a genetically altered serine acetyltransferase Appl Environ Microbiol 71 4149-4152
  • [6] Takagi H(2000)Identification and functional analysis of Escherichia coli cysteine desulfhydrase Mol Microbiol 36 1101-1112
  • [7] Datta P(2006)Identification of a major facilitator protein from Appl Environ Microbiol 72 4735-4742
  • [8] Park S(2009) involved in efflux of metabolites of the cysteine pathway Appl Microbiol Biotechnol 81 903-913
  • [9] Imlay JA(1990)Effect of drug transporter genes on cysteine export and overproduction in J Bacteriol 172 3358-3366
  • [10] Nakamori S(2000)The outer membrane TolC is involved in cysteine tolerance and overproduction in J Mol Microbiol Biotechnol 2 145-177