Uterine leiomyoma among women who conceived following fertility treatment

被引:3
作者
Biderman-Madar T. [1 ]
Sheiner E. [1 ]
Levy A. [2 ]
Potashnik G. [3 ]
Mazor M. [1 ]
机构
[1] Department of Obstetrics and Gynecology, Soroka University Medical Center, Ben Gurion University of the Negev, 151, Beer-Sheva
[2] Epidemiology and Health Services Evaluation Department, Soroka University Medical Center, Ben Gurion University of the Negev, Beer-Sheva
[3] Fertility and In-Vitro Fertilization Unit, Soroka University Medical Center, Ben Gurion University of the Negev, Beer-Sheva
关键词
Cesarean section; Fertility treatment; Uterine leiomyoma;
D O I
10.1007/s00404-005-0738-y
中图分类号
学科分类号
摘要
Objective: The objective was to determine if uterine leiomyoma increases the risk of cesarean section (CS) among women who conceived following fertility treatment. Study design: The study population consisted of all women who conceived after fertility treatment with singleton gestation and who delivered between the years 1988 and 1999 in the Soroka University Medical Center. A comparison was performed between patients with and without uterine leiomyomas. The Mantel-Haenszel procedure was used to obtain the weighted odds ratio (OR) for CS, while controlling for confounding variables. Results: During the study period 1,995 women conceived following fertility treatment. Of these, 63 patients had uterine leiomyomas (3.2%). Women treated for fertility with uterine leiomyomas had statistically significant higher rates of CS than those without uterine leiomyomas (61.9% vs. 28.1%, OR=4.2, 95% CI 2.4-7.2; P<0.001). Stratified analysis (the Mantel-Haenszel technique) was used to control for possible confounders, such as gestational diabetes, hypertensive disorders, maternal age, failure of labor to progress, placental abruption, malpresentation, hydramnios, oligohydramnios, and a previous CS. None of those variables changed the significant association or explained the higher incidence of CS in the uterine leiomyoma group. Conclusions: Uterine leiomyoma is an independent risk factor for CS among women who conceived following fertility treatment. © Springer-Verlag 2005.
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页码:218 / 222
页数:4
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