Antioxidant caffeic acid derivatives from leaves ofparthenocissus tricuspidata

被引:0
|
作者
Muhammad Saleem
Hyoung Ja Kim
Changbae Jin
Yong Sup Lee
机构
[1] Korea Institute of Science and Technology,Medicinal Chemistry Research Center, Division of Life Sciences
来源
Archives of Pharmacal Research | 2004年 / 27卷
关键词
Caffeic acid derivatives; Antioxidant activities;
D O I
暂无
中图分类号
学科分类号
摘要
Five caffeic acid derivatives; methyl ester of caffeoylglycolic acid (1), dimethyl ester of caffeoyltartaric acid (2), dimethyl ester of caffeoyltartronic acid (3), monomethyl ester of caffeoyltartronic acid (4), methyl ester of caffeic acid (5), and some other secondary metabolites including; quercetin, quercetin 3-O-β-D-glucuronide methyl ester, kaempferol, 3,5,7,4′-O-tetramethylkaempferol, β-sitosterol glucoside, 2α-hydroxyursolic acid and 2,24-dihydroxyursolic acid, have been isolated and characterized. All the isolated compounds were characterized with the help of NMR spectroscopy and mass spectrometry. Structure of compound3 was also confirmed by a single X-ray crystallographic technique. Isolates were evaluated for antioxidant activities and most of the tested compounds were found to be potent in DPPH free radical scavenging (IC50 = 4.56–14.17 μg/mL) and superoxide anion scavenging (IC50= 0.58–7.39 μg/mL) assays.
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页码:300 / 304
页数:4
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