Physiologically Based Pharmacokinetic Modeling of Rosuvastatin to Predict Transporter-Mediated Drug-Drug Interactions

被引：0
|
作者：
Nina Hanke
José David Gómez-Mantilla
Naoki Ishiguro
Peter Stopfer
Valerie Nock
机构：
[1] Boehringer Ingelheim Pharma GmbH & Co. KG,Translational Medicine & Clinical Pharmacology
[2] Nippon Boehringer Ingelheim Co. Ltd,Kobe Pharma Research Institute
来源：
Pharmaceutical Research | 2021年 / 38卷
关键词：
Physiologically based pharmacokinetic modeling (PBPK); Rosuvastatin; Drug-drug interactions (DDIs); Organic anion transporting polypeptide 1B1/1B3 (OATP1B1/1B3); Model-informed drug discovery and development (MID3);
D O I：
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摘要：
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页码：1645 / 1661
页数：16
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