A multimodality localization technique for radio-guided surgery

被引：8
作者：
Gulec S.A. [1 ]
Hoenie E. [1 ]
Rheinheimer K. [1 ]
机构：
[1] Goshen Cancer Institute, Goshen Health System, Goshen, IN
来源：
World Journal of Surgical Oncology | / 5卷 / 1期
关键词：
Chronic Granulomatous Disease; Localization Technique; Gamma Probe; Total Abdominal Colectomy; Gamma Probe Detection;
D O I：
10.1186/1477-7819-5-43
中图分类号：
学科分类号：
摘要：
Background: Intraoperative localization of image or endoscopy-detected lesions occasionally pose surgical challenges due to the small lesion size and/or difficult anatomic exposure. Identification of such lesions can be facilitated using a hand-held gamma probe with utilization of Tc-99m macroaggregate albumen (MAA) localization technique. The radiopharmaceutical injection can be performed using ultrasound (US) or endoscopy guidance. Case presentations: The clinical use of the Tc-99m MAA protocol gamma probe-guided surgery was discussed in three representative cases. Surgical indication was diagnostic exploration in two patients with suspicious lymphadenopathy, and determination of extent of surgical resection in a patient with polyposis. Lesion localization with 100 microcurie (3.7 MBq) Tc-99m MAA prior to surgical exploration resulted in definitive localization of lesions intraoperatively. Conclusion: The use Tc-99m MAA deposition technique at the site of surgical target is a highly efficient radio-guided surgery technique with definitive impact on the success of surgical exploration in selected indications. © 2007 Gulec et al; licensee BioMed Central Ltd.
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