Complete Response of Esophageal Cancer Achieved by Combination Therapy with 5-Fluorouracil, Low-Dose Cisplatin, and Radiation: Report of a Case

被引:0
作者
Shouji Shimoyama
Toshiro Konishi
Masaki Kawahara
Keiichi Hojo
Yuichi Takeda
Takahisa Nagayama
机构
[1] Department of Surgery,
[2] Showa General Hospital,undefined
[3] 2-450 Tenjincho,undefined
[4] Kodaira,undefined
[5] Tokyo 187,undefined
[6] Japan,undefined
[7] Department of Internal Medicine,undefined
[8] Showa General Hospital,undefined
[9] 2-450 Tenjincho,undefined
[10] Kodaira,undefined
[11] Tokyo 187,undefined
[12] Japan,undefined
[13] Department of Pathology,undefined
[14] Showa General Hospital,undefined
[15] 2-450 Tenjincho,undefined
[16] Kodaira,undefined
[17] Tokyo 187,undefined
[18] Japan,undefined
来源
Surgery Today | 1998年 / 28卷
关键词
Key Words: esophageal cancer; chemoradiation; cisplatin; 5-fluorouracil; radiosensitization;
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摘要
per day, from days 1–5 combined with the daily administration of low-dose cisplatin, 10 mg/m2 per day before each fraction of radiation, given as 2 Gy each time, throughout the entire treatment period of 3 weeks beginning on day 1. The benefits of our preoperative chemoradiation therapy included no severe side effects, down-staging and resectability of the tumor, as well as a pathological complete response, which could prolong the survival time. Our experience of this case prompts us to recommend the concurrent daily preoperative chemoradiation therapy for patients with locally advanced esophageal cancer.
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页码:1163 / 1167
页数:4
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