IRF4 – a factor for class switching and antibody secretion

被引：0
|
作者：
Simon Fillatreau
Andreas Radbruch
机构：
[1] Deutsches Rheuma-Forschungszentrum,
来源：
Nature Immunology | 2006年 / 7卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Cognate antigen triggers B cells to undergo antibody maturation and terminal differentiation into antibody-secreting plasma cells. The transcription factor IRF4, which is essential for early B cell development, is also influential at these later stages of B cell development and function.
引用
收藏
页码：704 / 706
页数：2
相关论文
共 50 条
  • [31] Requirement for the Transcription Factor LSIRF/IRF4 for Mature B and T Lymphocyte Function
    Mittrucker, Hans-Willi
    Matsuyama, Toshifumi
    Grossman, Alex
    Kundig, Thomas M.
    Potter, Julia
    Shahinian, Arda
    Wakeham, Andrew
    Patterson, Bruce
    Ohashi, Pamela S.
    Mak, Tak W.
    JOURNAL OF IMMUNOLOGY, 2017, 199 (11): : 3717 - 3720
  • [32] An activating mutation of interferon regulatory factor 4 (IRF4) in adult T-cell leukemia
    Cherian, Mathew A.
    Olson, Sydney
    Sundaramoorthi, Hemalatha
    Cates, Kitra
    Cheng, Xiaogang
    Harding, John
    Martens, Andrew
    Challen, Grant A.
    Tyagi, Manoj
    Ratner, Lee
    Rauch, Daniel
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 293 (18) : 6844 - 6858
  • [33] Prognostic significance of interferon regulating factor 4 (IRF4) in node-negative breast cancer
    Heimes, Anne-Sophie
    Madjar, K.
    Edlund, K.
    Battista, M. J.
    Almstedt, K.
    Gebhard, S.
    Foersch, S.
    Rahnenfuehrer, J.
    Brenner, W.
    Hasenburg, A.
    Hengstler, J. G.
    Schmidt, M.
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2017, 143 (07) : 1123 - 1131
  • [34] Prognostic impact of interferon regulating factor 4 (IRF4) in node-negative breast cancer
    Heimes, A. -S.
    van de Sandt, L.
    Edlund, K.
    Battista, M.
    Sicking, I.
    Almstedt, K.
    Lebrecht, A.
    Rahnenfuehrer, J.
    Hengstler, J. G.
    Schmidt, M.
    ONCOLOGY RESEARCH AND TREATMENT, 2016, 39 : 45 - 45
  • [35] Prognostic significance of interferon regulating factor 4 (IRF4) in node-negative breast cancer
    Anne-Sophie Heimes
    K. Madjar
    K. Edlund
    M. J. Battista
    K. Almstedt
    S. Gebhard
    S. Foersch
    J. Rahnenführer
    W. Brenner
    A. Hasenburg
    J. G. Hengstler
    M. Schmidt
    Journal of Cancer Research and Clinical Oncology, 2017, 143 : 1123 - 1131
  • [36] Interferon Regulatory Factor 4 (IRF4) Plays a Key Role in Osteoblast Differentiation of Postmenopausal Osteoporosis
    Wu, Xuan
    Yang, Cuicui
    Chen, Xiangxu
    Shan, Zhengming
    Wu, Xiaotao
    FRONTIERS IN BIOSCIENCE-LANDMARK, 2024, 29 (03):
  • [37] The Molecular Choreography of IRF4 and IRF8 with Immune System Partners
    Singh, Harinder
    Glasmacher, Elke
    Chang, Abraham B.
    Vander Lugt, Bryan
    IMMUNITY AND TOLERANCE, 2013, 78 : 101 - 104
  • [38] IRF4 silencing inhibits Hodgkin lymphoma cell proliferation, survival and CCL5 secretion
    Aldinucci, Donatella
    Celegato, Marta
    Borghese, Cinzia
    Colombatti, Alfonso
    Carbone, Antonino
    BRITISH JOURNAL OF HAEMATOLOGY, 2011, 152 (02) : 182 - 190
  • [39] Transcriptional Control of Adipose Lipid Handling by IRF4
    Eguchi, Jun
    Wang, Xun
    Yu, Songtao
    Kershaw, Erin E.
    Chiu, Patricia C.
    Dushay, Joanne
    Estall, Jennifer L.
    Klein, Ulf
    Maratos-Flier, Eleftheria
    Rosen, Evan D.
    CELL METABOLISM, 2011, 13 (03) : 249 - 259
  • [40] Structural determinants of the IRF4/DNA homodimeric complex
    Sundararaj, Srinivasan
    Seneviratne, Sandali
    Williams, Simon J.
    Enders, Anselm
    Casarotto, Marco G.
    NUCLEIC ACIDS RESEARCH, 2021, 49 (04) : 2255 - 2265
12345