IRF4 – a factor for class switching and antibody secretion

被引:0
|
作者
Simon Fillatreau
Andreas Radbruch
机构
[1] Deutsches Rheuma-Forschungszentrum,
来源
Nature Immunology | 2006年 / 7卷
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学科分类号
摘要
Cognate antigen triggers B cells to undergo antibody maturation and terminal differentiation into antibody-secreting plasma cells. The transcription factor IRF4, which is essential for early B cell development, is also influential at these later stages of B cell development and function.
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页码:704 / 706
页数:2
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