Construction of cuproptosis signature based on bioinformatics and experimental validation in clear cell renal cell carcinoma

Alvarez SW(2017)NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis Nature 551 639-643

Sviderskiy VO(2019)Immune suppression mediated by STAT4 deficiency promotes lymphatic metastasis in HNSCC Front Immunol 10 3095-918

Terzi EM(2020)Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma Nat Med 26 909-2083

Papagiannakopoulos T(2020)Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein Autophagy 16 2069-49

Moreira AL(2007)Inferential, robust non-negative matrix factorization analysis of microarray data Bioinformatics (Oxf, Engl) 23 44-1191

Adams S(2014)Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice Nat Cell Biol 16 1180-414

Sabatini DM(2019)Ferroptosis at the crossroads of cancer-acquired drug resistance and immune evasion Nat Rev Cancer 19 405-1056

Birsoy K(2020)Large-scale public data reuse to model immunotherapy response and resistance Genome Med 12 21-2849

Possemato R(2015)Going forward Nucleic Acids Res 43 1049-1370

Anderson K(2016)Complex heatmaps reveal patterns and correlations in multidimensional genomic data Bioinformatics (Oxf, Engl) 32 2847-953

Alvarez SW(2017)NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis Nature 551 639-643

Sviderskiy VO(2019)Immune suppression mediated by STAT4 deficiency promotes lymphatic metastasis in HNSCC Front Immunol 10 3095-918

Terzi EM(2020)Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma Nat Med 26 909-2083

Papagiannakopoulos T(2020)Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein Autophagy 16 2069-49

Moreira AL(2007)Inferential, robust non-negative matrix factorization analysis of microarray data Bioinformatics (Oxf, Engl) 23 44-1191

Adams S(2014)Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice Nat Cell Biol 16 1180-414

Sabatini DM(2019)Ferroptosis at the crossroads of cancer-acquired drug resistance and immune evasion Nat Rev Cancer 19 405-1056

Birsoy K(2020)Large-scale public data reuse to model immunotherapy response and resistance Genome Med 12 21-2849

Possemato R(2015)Going forward Nucleic Acids Res 43 1049-1370

Anderson K(2016)Complex heatmaps reveal patterns and correlations in multidimensional genomic data Bioinformatics (Oxf, Engl) 32 2847-953