Physiological diurnal variability and characteristics of the ocular pulse amplitude (OPA) with the dynamic contour tonometer (DCT-Pascal®)

被引:34
作者
Pourjavan S. [1 ]
Boëlle P.-Y. [2 ]
Detry-Morel M. [1 ]
De Potter P. [1 ]
机构
[1] Department of Ophthalmology, St. Luc University Hospital, Universite Catholique De Louvain
[2] Inserm, UMR S 707, Paris
关键词
Dynamic contour tonometry; Goldmann applanation tonometry; Intraocular pressure; Ocular pulse amplitude;
D O I
10.1007/s10792-007-9161-7
中图分类号
学科分类号
摘要
Purpose: The Pascal dynamic contour tonometer (DCT) allows measurement of intraocular pressure (IOP) independently of corneal properties. It records, simultaneously, haemodynamic IOP fluctuations and the difference between the systolic and the diastolic IOP corresponding to the ocular pulse amplitude (OPA). The OPA indirectly reflects choroidal perfusion and could be considered as an independent risk factor in glaucoma. We aimed to establish the physiological diurnal variability of the OPA and its correlations with other biophysical parameters because its characteristics remain partly unclear. Method: Prospective study including 52 eyes of 28 normal subjects with Goldmann applanation tonometry (GAT) IOPs < 22 mmHg. Subjects treated with systemic medications that could interfere with blood pressure or heart rate were excluded. IOP was measured at 9:00 am, 1:00 pm, and 4:00 pm by GAT and DCT. Two consecutive GAT followed by three consecutive DCT measurements were performed in each session by the same clinician (SP). Only DCT measurements with quality 1 and 2 were taken into account. Blood pressure, pulse rate, and central corneal thickness (CCT) were recorded after the last IOP measurements. Spearman correlation coefficient was used for assessment of correlations. Results: Mean age was 40 ± 14 years. Mean DCT values were significantly higher than GAT readings (mean = 16.8 ± 2.0 vs. 15.2 ± 2.8 mmHg, P < 0.02). The mean OPA was 2.2 ± 0.7 mmHg (range: 1-3.4 mmHg). The mean amplitude of diurnal OPA fluctuations was 0.4 mmHg. There was no significant difference in the mean OPA values at each time of the diurnal curve. The intraclass correlation (ICC) of only one OPA measurement in relation to part of total variance due to inter-measurement variation was 78%. Averaging over three independent readings of OPA improved ICC to 91%. The OPA was correlated with GAT (r = 0.31, P < 0.0001) and DCT IOP measurements (r = 0.49, P < 0.0001). It was correlated neither with blood pressure nor with age. OPA values of both eyes of the same individual were highly correlated (r = 0.89, P < 0.0001). Conclusion: In normal healthy eyes, the ocular pulse amplitude remains stable during normal outpatient office hours and was not correlated with blood pressure or age of patients. © Springer Science+Business Media B.V. 2007.
引用
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页码:357 / 360
页数:3
相关论文
共 11 条
[1]  
Kanngiesser H.E., Kniestedt C., Robert Y.C.A., Dynamic contour tonometry. Presentation of a new tonometer, J Glaucoma, 14, pp. 344-350, (2005)
[2]  
Hoffmann E.M., Grus F.-H., Pfeiffer N., Intraocular pressure and ocular pulse amplitude using dynamic contour tonometry and contact lens tonometry, BMC Ophthalmol, 4, pp. 1-7, (2004)
[3]  
Schwenn O., Troost R., Vogel A., Grus F., Beck S., Pfeiffer N., Ocular pulse amplitude in patients with open angle glaucoma, normal tension glaucoma, and ocular hypertension, Br J Ophthalmol, 86, pp. 981-984, (2002)
[4]  
Lachkar Y., I have tested for you. The contour tonometer, IOP analysis using "Dynamic Contour Tonometry, J Fr Ophtalmol, 29, pp. 2532-2535, (2006)
[5]  
Pache M., Wilmsmeyer S., Lautebach S., Funk J., Dynamic contour tonometry versus Goldmann applanation tonometry: A comparative study, Graefe's Arch Clin Exp Ophthalmol, 243, pp. 763-767, (2005)
[6]  
Kaufmann C., Bachmann L.M., Thiel M.A., Comparison of dynamic contour tonometry with Goldmann applanation tonometry, IOVS, 45, 9, pp. 3118-3121, (2004)
[7]  
Doyle A., Lachkar M.D., Comparison of dynamic contour tonometry with Goldmann applanation tonometry over a wide range of central corneal thickness, J Glaucoma, 14, 4, pp. 288-292, (2005)
[8]  
Ku J.Y.F., Danesh-Meyer H.V., Craig J.P., Gamble G.D., McGhee C.N.J., Comparison of intraocular pressure measured by Pascal dynamic contour tonometry and Goldmann applanation tonometry, Eye, 20, pp. 191-198, (2006)
[9]  
Siganos D., Papastergiou G.I., Moedas C., Assessment of the Pascal dynamic contour tonometer in monitoring intraocular pressure in unoperated eyes and eyes after LASIK, J Cataract Refract Surg, 30, pp. 764-771, (2004)
[10]  
Punjabi O.S., Ho H.K., Kniestedt C., Bostrom A.G., Stamper R.L., Lin S.C., Intraocular pressure and ocular pulse amplitude comparisons in different types of glaucoma using dynamic contour tonometry, Curr Eye Res, 31, 10, pp. 851-862, (2006)