Increased susceptibility of CD4+ T cells from elderly individuals to HIV-1 infection and apoptosis is associated with reduced CD4 and enhanced CXCR4 and FAS surface expression levels

被引：0
|
作者：
Anke Heigele
Simone Joas
Kerstin Regensburger
Frank Kirchhoff
机构：
[1] Ulm University Medical Center,Institute of Molecular Virology
来源：
Retrovirology | / 12卷
关键词：
HIV; Aging; T cell subsets; CXCR4; FAS; Apoptosis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [31] HIV-1 Vpu Downregulates Tim-3 from the Surface of Infected CD4+ T Cells
    Prevost, Jeremie
    Edgar, Cassandra R.
    Richard, Jonathan
    Trothen, Steven M.
    Jacob, Rajesh Abraham
    Mumby, Mitchell J.
    Pickering, Suzanne
    Dube, Mathieu
    Kaufmann, Daniel E.
    Kirchhoff, Frank
    Neil, Stuart J. D.
    Finzi, Andres
    Dikeakos, Jimmy D.
    JOURNAL OF VIROLOGY, 2020, 94 (07)
  • [32] Quantifying Susceptibility of CD4+ Stem Memory T-Cells to Infection by Laboratory Adapted and Clinical HIV-1 Strains
    Flynn, Jacqueline K.
    Paukovics, Geza
    Cashin, Kieran
    Borm, Katharina
    Ellett, Anne
    Roche, Michael
    Jakobsen, Martin R.
    Churchill, Melissa J.
    Gorry, Paul R.
    VIRUSES-BASEL, 2014, 6 (02): : 709 - 726
  • [33] Preferential susceptibility of Th9 and Th2 CD4+ T cells to X4-tropic HIV-1 infection
    Orlova-Fink, Nina
    Chowdhury, Fatema Z.
    Sun, Xiaoming
    Harrington, Sean
    Rosenberg, Eric S.
    Yu, Xu G.
    Lichterfeld, Mathias
    AIDS, 2017, 31 (16) : 2211 - 2215
  • [34] HIV-1 and HIV-2 infections induce autophagy in Jurkat and CD4+ T cells
    Wang, Xue
    Gao, Yamei
    Tan, Jiying
    Devadas, Krishnakumar
    Ragupathy, Viswanath
    Takeda, Kazuyo
    Zhao, Jiangqin
    Hewlett, Indira
    CELLULAR SIGNALLING, 2012, 24 (07) : 1414 - 1419
  • [35] Death and survival of gut CD4 T cells following HIV-1 infection ex vivo
    Mickens, Kaylee L.
    Dillon, Stephanie M.
    Guo, Kejun
    Thompson, Ashley N.
    Barrett, Bradley S.
    Wood, Cheyret
    Kechris, Katerina
    Santiago, Mario L.
    Wilson, Cara C.
    PNAS NEXUS, 2024, 3 (11):
  • [36] Efficient HIV-1 Trans Infection of CD4+ T Cells Occurs in the Presence of Antiretroviral Therapy
    Rappocciolo, Giovanna
    Sluis-Cremer, Nicolas
    Rinaldo, Charles R.
    OPEN FORUM INFECTIOUS DISEASES, 2019, 6 (07):
  • [37] Depletion of naive CD4 T cells by CXCR4-using HIV-1 variants occurs mainly through increased T-cell death and activation
    Hazenberg, MD
    Otto, SA
    Hamann, D
    Roos, MTL
    Schuitemaker, H
    de Boer, RJ
    Miedema, F
    AIDS, 2003, 17 (10) : 1419 - 1424
  • [38] Increased HLA-DR expression on peripheral blood monocytes in subsets of subjects with primary HIV infection is associated with elevated CD4 T-cell apoptosis and CD4 T-cell depletion
    Gascon, RL
    Narváez, AB
    Zhang, RZ
    Kahn, JO
    Hecht, FM
    Herndier, BG
    McGrath, MS
    JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2002, 30 (02) : 146 - 153
  • [39] Fas (CD95) expression on CD4+ T cells from HIV-infected patients increases with disease progression
    Aries, SP
    Schaaf, B
    Muller, C
    Dennin, RH
    Dalhoff, K
    JOURNAL OF MOLECULAR MEDICINE-JMM, 1995, 73 (12): : 591 - 593
  • [40] HIV-1 Expression Within Resting CD4+ T Cells After Multiple Doses of Vorinostat
    Archin, Nancy M.
    Bateson, Rosalie
    Tripathy, Manoj K.
    Crooks, Amanda M.
    Yang, Kuo-Hsiung
    Dahl, Noelle P.
    Kearney, Mary F.
    Anderson, Elizabeth M.
    Coffin, John M.
    Strain, Matthew C.
    Richman, Douglas D.
    Robertson, Kevin R.
    Kashuba, Angela D.
    Bosch, Ronald J.
    Hazuda, Daria J.
    Kuruc, Joann D.
    Eron, Joseph J.
    Margolis, David M.
    JOURNAL OF INFECTIOUS DISEASES, 2014, 210 (05): : 728 - 735
12345