Multiple PIK3CA mutation clonality correlates with outcomes in taselisib + fulvestrant-treated ER+/HER2–, PIK3CA-mutated breast cancers

被引：0
作者：
Katherine E. Hutchinson
Jessica W. Chen
Heidi M. Savage
Thomas J. Stout
Frauke Schimmoller
Javier Cortés
Susan Dent
Nadia Harbeck
William Jacot
Ian Krop
Sally E. Trabucco
Smruthy Sivakumar
Ethan S. Sokol
Timothy R. Wilson
机构：
[1] Oncology Biomarker Development,Product Development Oncology
[2] Genentech,Department of Medicine, Faculty of Biomedical and Health Sciences
[3] Inc.,Duke Cancer Institute
[4] Genentech,Breast Center, Department Gynecology and Obstetrics and Comprehensive Cancer Center (CCC) Munich
[5] Inc.,Institut du Cancer de Montpellier (ICM) Val d’Aurelle
[6] International Breast Cancer Center (IBCC),undefined
[7] Pangaea Oncology,undefined
[8] Quironsalud Group,undefined
[9] Universidad Europea de Madrid,undefined
[10] Duke University,undefined
[11] Ludwig-Maximilians-University (LMU) Hospital,undefined
[12] Montpellier University,undefined
[13] Yale Cancer Center,undefined
[14] Foundation Medicine,undefined
[15] Inc,undefined
来源：
Genome Medicine | / 15卷
关键词：
Double ; mutation; Clonal; Taselisib; PI3K inhibitor; Breast cancer; ctDNA; PI3K signaling;
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