Targeting the m6A mRNA demethylase FTO suppresses vascular endothelial growth factor release and choroidal neovascularization

被引：0
作者：
Shao-bin Wang
Yosuke Nagasaka
Dionne Argyle
Ayami Nagasaka
Praveen Yerramothu
Bradley D. Gelfand
Jayakrishna Ambati
机构：
[1] University of Virginia School of Medicine,Center for Advanced Vision Science
[2] University of Virginia School of Medicine,Department of Ophthalmology
[3] University of Virginia School of Medicine,Department of Biomedical Engineering
[4] University of Virginia School of Medicine,Department of Pathology
[5] University of Virginia School of Medicine,Department of Microbiology, Immunology, and Cancer Biology
来源：
Signal Transduction and Targeted Therapy | / 8卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
[21]   Natural history of choroidal neovascularization induced by vascular endothelial growth factor in the primate [J].
Cui, JZ ;
Kimura, H ;
Spee, C ;
Thumann, G ;
Hinton, DR ;
Ryan, SJ .
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2000, 238 (04) :326-333
[22]   A novel vascular endothelial growth factor receptor 2 inhibitor, SU11248, suppresses choroidal neovascularization in vivo [J].
Takahashi, Hidenori ;
Obata, Ryo ;
Tamaki, Yasuhiro .
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2006, 22 (04) :213-218
[23]   Vascular Endothelial Growth Factor Gene and the Response to Anti-Vascular Endothelial Growth Factor Treatment for Choroidal Neovascularization in High Myopia [J].
Miyake, Masahiro ;
Yamashiro, Kenji ;
Akagi-Kurashige, Yumiko ;
Kumagai, Kyoko ;
Nakata, Isao ;
Nakanishi, Hideo ;
Oishi, Akio ;
Tsujikawa, Akitaka ;
Yamada, Ryo ;
Matsuda, Fumihiko ;
Yoshimura, Nagahisa .
OPHTHALMOLOGY, 2014, 121 (01) :225-233
[24]   An m6A Demethylase, FTO Mediates Post-transcriptional mRNA Modifications to Regulate Cardiac and Cardiomyocyte Function [J].
Mathiyalagan, Prabhu ;
Adamiak, Marta ;
Mayourian, Joshua ;
Liang, Yaxuan ;
Sassi, Yassine ;
Agarwal, Neha ;
Jha, Divya ;
Ishikawa, Kiyotake ;
Zhang, Shihong ;
Kohlbrenner, Erik ;
Yin, Xiaoke ;
Chepurko, E. ;
Chen, J. ;
Trivieri, M. G. ;
Singh, R. ;
Mayr, M. ;
Fish, K. ;
Lebeche, D. ;
Hajjar, R. J. ;
Sahoo, S. .
CIRCULATION RESEARCH, 2018, 123
[25]   m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade [J].
Seungwon Yang ;
Jiangbo Wei ;
Yan-Hong Cui ;
Gayoung Park ;
Palak Shah ;
Yu Deng ;
Andrew E. Aplin ;
Zhike Lu ;
Seungmin Hwang ;
Chuan He ;
Yu-Ying He .
Nature Communications, 10
[26]   Expression of vascular endothelial growth factor and its receptor (KDR/flk-1) mRNA in experimental choroidal neovascularization [J].
Wada, M ;
Ogata, N ;
Otsuji, T ;
Uyama, M .
CURRENT EYE RESEARCH, 1999, 18 (03) :203-213
[27]   Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis [J].
Cui, Yan-Hong ;
Yang, Seungwon ;
Wei, Jiangbo ;
Shea, Christopher R. ;
Zhong, Wen ;
Wang, Fang ;
Shah, Palak ;
Kibriya, Muhammad G. ;
Cui, Xiaolong ;
Ahsan, Habibul ;
He, Chuan ;
He, Yu-Ying .
NATURE COMMUNICATIONS, 2021, 12 (01)
[28]   Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis [J].
Yan-Hong Cui ;
Seungwon Yang ;
Jiangbo Wei ;
Christopher R. Shea ;
Wen Zhong ;
Fang Wang ;
Palak Shah ;
Muhammad G. Kibriya ;
Xiaolong Cui ;
Habibul Ahsan ;
Chuan He ;
Yu-Ying He .
Nature Communications, 12
[29]   m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade [J].
Yang, Seungwon ;
Wei, Jiangbo ;
Cui, Yan-Hong ;
Parka, Gayoung ;
Shah, Palak ;
Deng, Yu ;
Aplin, Andrew E. ;
Lu, Zhike ;
Hwang, Seungmin ;
He, Chuan ;
He, Yu-Ying .
NATURE COMMUNICATIONS, 2019, 10 (1)
[30]   Correction: The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging [J].
Zhong-xin Jiang ;
Yi-ning Wang ;
Zi-yuan Li ;
Zhi-hui Dai ;
Yi He ;
Kun Chu ;
Jia-yi Gu ;
Yi-Xuan Ji ;
Ning-xia Sun ;
Fu Yang ;
Wen Li .
Cell Death & Disease, 12
12345