Targeting the m6A mRNA demethylase FTO suppresses vascular endothelial growth factor release and choroidal neovascularization

被引：0
|
作者：
Shao-bin Wang
Yosuke Nagasaka
Dionne Argyle
Ayami Nagasaka
Praveen Yerramothu
Bradley D. Gelfand
Jayakrishna Ambati
机构：
[1] University of Virginia School of Medicine,Center for Advanced Vision Science
[2] University of Virginia School of Medicine,Department of Ophthalmology
[3] University of Virginia School of Medicine,Department of Biomedical Engineering
[4] University of Virginia School of Medicine,Department of Pathology
[5] University of Virginia School of Medicine,Department of Microbiology, Immunology, and Cancer Biology
来源：
Signal Transduction and Targeted Therapy | / 8卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] Targeting the m6A mRNA demethylase FTO suppresses vascular endothelial growth factor release and choroidal neovascularization
    Wang, Shao-bin
    Nagasaka, Yosuke
    Argyle, Dionne
    Nagasaka, Ayami
    Yerramothu, Praveen
    Gelfand, Bradley D.
    Ambati, Jayakrishna
    SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 8 (01)
  • [2] Targeting the oncogenic m6A demethylase FTO suppresses tumourigenesis and potentiates immune response in hepatocellular carcinoma
    Chen, Ao
    Zhang, Vanilla Xin
    Zhang, Qingyang
    Sze, Karen Man-Fong
    Tian, Lu
    Huang, Hongyang
    Wang, Xia
    Lee, Eva
    Lu, Jingyi
    Lyu, Xueying
    Lee, Man-Fong Joyce
    Wong, Chun Ming
    Ho, Daniel Wai-Hung
    Ng, Irene Oi-Lin
    GUT, 2025, 74 (01) : 90 - 102
  • [3] The m6A demethylase FTO promotes the growth of lung cancer cells by regulating the m6A level of USP7 mRNA
    Li, Jie
    Han, Yi
    Zhang, Hongmei
    Qian, Zhe
    Jia, Wenyun
    Gao, Yuan
    Zheng, Hua
    Li, Baolan
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 512 (03) : 479 - 485
  • [4] Targeting m6A mRNA demethylase FTO alleviates manganese-induced cognitive memory deficits in mice
    Wen, Yi
    Fu, Zhushan
    Li, Jiashuo
    Liu, Mingyue
    Wang, Xinmiao
    Chen, Jingqi
    Chen, Yue
    Wang, Haocheng
    Wen, Sihang
    Zhang, Ke
    Deng, Yu
    JOURNAL OF HAZARDOUS MATERIALS, 2024, 476
  • [5] Comprehensive analysis of the m6A demethylase FTO in endothelial dysfunction by MeRIP sequencing
    Shan, Li
    Tao, Meng
    Zhang, Wei
    Zhao, Jin-Dong
    Liu, Xiao-Chuang
    Fang, Zhao-Hui
    Gao, Jia-Rong
    EXPERIMENTAL CELL RESEARCH, 2024, 442 (02)
  • [6] Vascular endothelial growth factor expression in choroidal neovascularization in rats
    Yi, XJ
    Ogata, N
    Komada, M
    Yamamoto, C
    Takahashi, K
    Omori, K
    Uyama, M
    GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 1997, 235 (05) : 313 - 319
  • [7] Vascular endothelial growth factor expression in choroidal neovascularization in rats
    Xianjin Yi
    Nahoko Ogata
    Masayuki Komada
    Chikako Yamamoto
    Kanji Takahashi
    Koichiro Omori
    Masanobu Uyama
    Graefe's Archive for Clinical and Experimental Ophthalmology, 1997, 235 : 313 - 319
  • [8] Expression of vascular endothelial growth factor in experimental choroidal neovascularization
    Ishibashi, T
    Hata, Y
    Yoshikawa, H
    Nakagawa, K
    Sueishi, K
    Inomata, H
    GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 1997, 235 (03) : 159 - 167
  • [9] Expression of vascular endothelial growth factor in experimental choroidal neovascularization
    Ogata, N
    Yi, XJ
    Yamanoto, C
    Uyama, M
    Omori, K
    Komada, M
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1996, 37 (03) : 589 - 589
  • [10] Expression of vascular endothelial growth factor in experimental choroidal neovascularization
    Tatsuro Ishibashi
    Yasuaki Hata
    Hiroshi Yoshikawa
    Kazunori Nakagawa
    Katsuo Sueishi
    Hajime Inomata
    Graefe's Archive for Clinical and Experimental Ophthalmology, 1997, 235 : 159 - 167
12345