Autism Symptomatology in Boys with Fragile X Syndrome: A Cross Sectional Developmental Trajectories Comparison with Nonsyndromic Autism Spectrum Disorder

被引：0
作者：
Angela John Thurman
Andrea McDuffie
Sara T. Kover
Randi J. Hagerman
Leonard Abbeduto
机构：
[1] University of California Davis,MIND Institute
[2] University of California Davis,Department of Psychiatry and Behavioral Sciences
[3] University of Washington,Department of Speech and Hearing Sciences
[4] University of California Davis,Department of Pediatrics
来源：
Journal of Autism and Developmental Disorders | 2015年 / 45卷
关键词：
Fragile X syndrome; Autism spectrum disorder; Behavioral phenotype; Nonverbal cognition; Expressive vocabulary; Developmental trajectory;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Although males with fragile X syndrome (FXS) are frequently described as demonstrating autism symptomatology, there is much debate regarding whether the behavioral symptoms representing the core domains of autism are the result of the same or different underlying neurological/psychological mechanisms. The present study used a cross-sectional developmental trajectories approach to compare the profiles of autism symptomatology relative to chronological age (CA), nonverbal IQ, and expressive vocabulary ability between individuals with FXS and individuals with nonsyndromic ASD. Results suggest that the onset of autism symptoms and their developmental trajectories in males with FXS differ in important ways as a function of CA, nonverbal cognitive ability, and expressive vocabulary relative to males with nonsyndromic ASD. Theoretical and clinical implications are discussed.
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页码：2816 / 2832
页数：16
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