Selective recyclization of 2-aroylmethyl-1H-benzimidazole hydrazones by condensation with dimethylformamide

被引：1

作者：

Dzvinchuk I.B. ^{[1
]}

Vypirailenko A.V. ^{[1
]}

Lozinskii M.O. ^{[1
]}

机构：

[1] Institute of Organic Chemistry, Ukrainian Academy of Sciences

来源：

Chemistry of Heterocyclic Compounds | 2001年 / 37卷 / 09期

关键词：

Benzimidazoles; Condensation; Hydrazones; Pyrazoles; Recyclization; Selectivity;

D O I：

10.1023/A:1013223531612

中图分类号：

学科分类号：

摘要：

2-Aroylmethyl-1H-benzimidazole hydrazones are converted to 1-[pyrazol-3(5)-yl]benzimidazoles by refluxing in dimethylformamide in the presence of trifluoroacetic acid. The same products are obtained by refluxing 2-aroylmethyl-1H-benzimidazoles with hydrazine hydrochloride in dimethylformamide. Electron donor substituents in the para position of the aryl fragment of the starting compounds do not favor the reaction.

引用

页码：1096 / 1101

页数：5

共 8 条

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