Update on the Epidemiology of Melanoma

被引：86
作者：
Chen S.T. [1 ]
Geller A.C. [2 ]
Tsao H. [1 ]
机构：
[1] Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, Bartlett Hall, 6th floor
[2] Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA, 02115, Kresge Building, 701A
来源：
Current Dermatology Reports | 2013年 / 2卷 / 1期
关键词：
Cancer; Epidemiology; Genetics; Melanoma;
D O I：
10.1007/s13671-012-0035-5
中图分类号：
学科分类号：
摘要：
Cutaneous malignant melanoma (CMM) has been increasing steadily in incidence during the past 30 years. Recent studies have explored associations between CMM and varying physiologic risk factors, such as nevi or hair and eye color, in addition to historical features, such as a personal history of nonmelanoma skin cancer (NMSC), childhood cancers, Parkinson's disease, hormone exposure, and family history of CMM. Genome-wide association studies also have uncovered many genetic determinants of CMM risk. Ultimately, ultraviolet (UV) radiation exposure remains the most important modifiable risk factor for CMM. Organ transplant recipients and nonsteroidal anti-inflammatory usage also may play a role. Whereas risk factors are important to identify, effective campaigns to reduce the burden of disease through early detection and prevention are essential. We present detailed data regarding these facets of care for the CMM patient and provide an update on the epidemiology of CMM. © 2013 Springer Science+Business Media New York.
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页码：24 / 34
页数：10
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