Expression of a recombinant FLT3 ligand and its emtansine conjugate as a therapeutic candidate against acute myeloid leukemia cells with FLT3 expression

[1] De Kouchkovsky I(2016)Acute myeloid leukemia: a comprehensive review and 2016 update Blood Cancer J 6 e441-e-749

[2] Abdul-Hay M(2019)Acute myeloid leukemia, version 3.2019, NCCN clinical practice guidelines in oncology J Natl Comp Cancer Netw JNCCN. 17 721-312

[3] Tallman M(2020)Gene mutational analysis by NGS and its clinical significance in patients with myelodysplastic syndrome and acute myeloid leukemia Exp Hematol Oncol 9 2-1542

[4] Wang E(2020)Clinical implications of recurrent gene mutations in acute myeloid leukemia Exp Hematol Oncol 9 4-3390

[5] Altman J(2019)Targeting FLT3 mutations in AML: review of current knowledge and evidence Leukemia 33 299-1096

[6] Appelbaum F(2002)The roles of FLT3 in hematopoiesis and leukemia Blood 100 1532-1918

[7] Bhatt V(1996)FLT3 receptor expression on the surface of normal and malignant human hematopoietic cells Blood 88 3383-58

[8] Bixby D(1996)Expression of the hematopoietic growth factor receptor FLT3 (STK-1/Flk2) in human leukemias Blood 87 1089-753

[9] Yu J(1996)Internal tandem duplication of the flt3 gene found in acute myeloid leukemia Leukemia 10 1911-464

[10] Li Y(2002)Gemtuzumab ozogamicin, a potent and selective anti-CD33 antibody-calicheamicin conjugate for treatment of acute myeloid leukemia Bioconjug Chem 13 47-4851

[1] De Kouchkovsky I(2016)Acute myeloid leukemia: a comprehensive review and 2016 update Blood Cancer J 6 e441-e-749

[2] Abdul-Hay M(2019)Acute myeloid leukemia, version 3.2019, NCCN clinical practice guidelines in oncology J Natl Comp Cancer Netw JNCCN. 17 721-312

[3] Tallman M(2020)Gene mutational analysis by NGS and its clinical significance in patients with myelodysplastic syndrome and acute myeloid leukemia Exp Hematol Oncol 9 2-1542

[4] Wang E(2020)Clinical implications of recurrent gene mutations in acute myeloid leukemia Exp Hematol Oncol 9 4-3390

[5] Altman J(2019)Targeting FLT3 mutations in AML: review of current knowledge and evidence Leukemia 33 299-1096

[6] Appelbaum F(2002)The roles of FLT3 in hematopoiesis and leukemia Blood 100 1532-1918

[7] Bhatt V(1996)FLT3 receptor expression on the surface of normal and malignant human hematopoietic cells Blood 88 3383-58

[8] Bixby D(1996)Expression of the hematopoietic growth factor receptor FLT3 (STK-1/Flk2) in human leukemias Blood 87 1089-753

[9] Yu J(1996)Internal tandem duplication of the flt3 gene found in acute myeloid leukemia Leukemia 10 1911-464

[10] Li Y(2002)Gemtuzumab ozogamicin, a potent and selective anti-CD33 antibody-calicheamicin conjugate for treatment of acute myeloid leukemia Bioconjug Chem 13 47-4851