Exploring the causal effect of maternal pregnancy adiposity on offspring adiposity: Mendelian randomisation using polygenic risk scores

被引：0
作者：
Tom A. Bond
Rebecca C. Richmond
Ville Karhunen
Gabriel Cuellar-Partida
Maria Carolina Borges
Verena Zuber
Alexessander Couto Alves
Dan Mason
Tiffany C. Yang
Marc J. Gunter
Abbas Dehghan
Ioanna Tzoulaki
Sylvain Sebert
David M. Evans
Alex M. Lewin
Paul F. O’Reilly
Deborah A. Lawlor
Marjo-Riitta Järvelin
机构：
[1] Imperial College London,Department of Epidemiology and Biostatistics
[2] Imperial College London,MRC
[3] The University of Queensland,PHE Centre for Environment and Health, School of Public Health
[4] University of Bristol,The University of Queensland Diamantina Institute
[5] University of Bristol,MRC Integrative Epidemiology Unit
[6] University of Oulu,Population Health Sciences, Bristol Medical School
[7] University of Oulu,Center for Life
[8] 23andMe,course Health Research, Faculty of Medicine
[9] Inc.,Research Unit of Mathematical Sciences
[10] University of Cambridge,MRC Biostatistics Unit, School of Clinical Medicine
[11] University of Surrey,School of Biosciences and Medicine, Faculty of Health and Medical Sciences
[12] Bradford Teaching Hospitals NHS Foundation Trust,Born in Bradford, Bradford Institute for Health Research
[13] IARC,Section of Nutrition and Metabolism
[14] University of Ioannina Medical School,Department of Hygiene and Epidemiology
[15] University of Queensland,Institute for Molecular Bioscience
[16] London School of Hygiene and Tropical Medicine,Department of Medical Statistics
[17] Icahn School of Medicine at Mount Sinai,Genetics and Genomic Sciences
[18] Oulu University Hospital,Unit of Primary Care
[19] Brunel University London,Department of Life Sciences, College of Health and Life Sciences
来源：
BMC Medicine | / 20卷
关键词：
Obesity; BMI; Pregnancy; Child; Maternal; Offspring; DOHaD; Mendelian randomisation;
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[1]  
Lawlor DA(2013)The Society for Social Medicine John Pemberton Lecture 2011. Developmental overnutrition—an old hypothesis with new importance? Int J Epidemiol 42 7-29
[2]  
Godfrey KM(2017)Influence of maternal obesity on the long-term health of offspring Lancet Diabetes Endocrinol 5 53-64
[3]  
Reynolds RM(2018)Origins of lifetime health around the time of conception: causes and consequences Lancet. 391 1842-1852
[4]  
Prescott SL(2019)Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: an individual participant data meta-analysis PLoS Med 16 f4539-2151
[5]  
Nyirenda M(2019)The association between maternal body mass index and child obesity: a systematic review and meta-analysis PLoS Med 16 2137-639
[6]  
Jaddoe VWV(2013)Maternal obesity during pregnancy and premature mortality from cardiovascular event in adult offspring: follow-up of 1 323 275 person years BMJ. 347 627-1886
[7]  
Eriksson JG(2018)Developmental programming of obesity and diabetes in mouse, monkey, and man in 2018: where are we headed? Diabetes. 67 1866-92
[8]  
Broekman BFP(2012)Maternal obesity, gestational weight gain and diet as determinants of offspring long term health Best Pract Res Clin Endocrinol Metab 26 83-41
[9]  
Fleming TP(2016)Triangulation in aetiological epidemiology Int J Epidemiol 45 32-691
[10]  
Watkins AJ(2012)Parent-offspring body mass index associations in the Norwegian Mother and Child Cohort Study: a family-based approach to studying the role of the intrauterine environment in childhood adiposity Am J Epidemiol 176 683-578
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