Pivoting of microtubules around the spindle pole accelerates kinetochore capture

被引：0
作者：
Iana Kalinina
Amitabha Nandi
Petrina Delivani
Mariola R. Chacón
Anna H. Klemm
Damien Ramunno-Johnson
Alexander Krull
Benjamin Lindner
Nenad Pavin
Iva M. Tolić-Nørrelykke
机构：
[1] Max Planck Institute of Molecular Cell Biology and Genetics,Department of Physics
[2] Max Planck Institute for the Physics of Complex Systems,undefined
[3] Faculty of Science,undefined
[4] University of Zagreb,undefined
[5] Present address: European Molecular Biology Laboratory,undefined
[6] Meyerhofstrasse 1,undefined
[7] 69117 Heidelberg,undefined
[8] Germany (I.K.); Department of Molecular,undefined
[9] Cellular and Developmental Biology,undefined
[10]  Yale University,undefined
[11]  New Haven,undefined
[12] Connecticut 06520,undefined
[13] USA (A.N.); Bernstein Center for Computational Neuroscience Berlin and Physics Department of Humboldt University Berlin,undefined
[14] 10115 Berlin,undefined
[15] Germany (B.L.),undefined
来源：
Nature Cell Biology | 2013年 / 15卷
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摘要：
To segregate chromosomes, spindle microtubules must attach to chromosomes through kinetochores, in a process involving several types of microtubule behaviour. Tolic-Norrelykke and colleagues find that fission yeast microtubules rapidly rotate around the spindle poles, and mathematical modelling confirms that this random microtubule movement facilitates kinetochore capture.
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页码：82 / 87
页数：5
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