50 years of protein acetylation: from gene regulation to epigenetics, metabolism and beyond

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作者
Eric Verdin
Melanie Ott
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[1] Eric Verdin and Melanie Ott are at the Gladstone Institutes,
[2] University of California,undefined
[3] San Francisco,undefined
[4] 1650 Owens Street,undefined
[5] San Francisco,undefined
[6] California 94158,undefined
[7] USA.,undefined
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摘要
The year 2014 marks the 50th anniversary of the discovery of protein acetylation. In this Timeline article, Verdin and Ott discuss the identification of this modification, of its regulatory enzymes and of the roles of acetylation in transcription and other cellular processes, and provide an outlook on the future of the field.
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页码:258 / 264
页数:6
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